Index Catalog // ScholarsArchive@OSU

Chemopreventative and chemotherapeutic properties of whole cruciferous vegetables and phytochemical components in acute T-cell lymphoblastic leukemia/lymphoma

Creator:: Shorey, Lyndsey E.
Abstract:: Acute lymphoblastic leukemia (ALL) encompasses a spectrum of lymphoid progenitors that have undergone malignant transformation and clonal proliferation at various stages of differentiation. Some cases of ALL have been documented to have prenatal origins and in particular neonatal exposure to various environmental pollutants is associated with increased disease risk, including...
Resource Type:: Dissertation
Full Text:: Acute T-cell Lymphoblastic Leukemia/lymphoma. Abstract approved: David E. Williams

In vivo detoxification of acetic acid in Saccharomyces cerevisiae

Creator:: Ding, Jun
Abstract:: The studies described in this thesis were motivated by ongoing efforts to develop lignocellulosic biomass as an efficient and practical source of renewable energy. Enormous problems complicate these efforts to reduce reliance on greenhouse gas-generating fossil fuels. Simply obtaining the fermentable sugars available in the cellulose and hemicellulose components of...
Resource Type:: Dissertation
Full Text:: cerevisiae Abstract approved: Alan T. Bakalinsky The studies described in this thesis

Perceptions on Spalted Wood: The Influence of Historic Spalting Patterns and Valuation of Spalted Wood Around the World.

Creator:: Vega Gutiérrez, Patricia T.
Abstract:: During the 1400s – 1600s, spalted wood was an expensive commodity used in marquetry style artworks across primarily Germany and Italy. It fell out of favor during the Industrial Revolution, but is currently experiencing resurgence in popularity with US woodturners. How spalted wood is used, and what types of spalted...
Resource Type:: Dissertation

Secondary Metabolism in Tolypocladium : Characterization, Ecology, Evolution and Regulation

Creator:: Blount, Rheannon Rua
Abstract:: An increased understanding of secondary metabolism in fungi is important for both biological and societal reasons. The ascomycete genus, Tolypocladium, is an ideal system to explore secondary metabolism characterization, ecology, evolution and regulation. The genus produces and has the genomic potential to produce a wide array of metabolites. Paired with...
Resource Type:: Dissertation
Full Text:: synthetase, is only found in one well-supported clade which contains the insect pathogen, T. inflatum, as

Roles of homeodomain transcription factors during organogenesis

Creator:: Xu, Jun
Abstract:: The spatial and temporal patterning of sequence specific transcription factors (SSTFs) contributes to cell type specification and organ formation during embryogenesis. Homeodomain transcription factors are evolutionally conserved among invertebrate and vertebrate animals. They are responsible for body segmentation and organogenesis. Lbx1 and Pitx2 both are homeodomain transcription factors contributing to...
Resource Type:: Dissertation
Full Text:: : Chrissa Kioussi Michael K. Gross The spatial and temporal patterning of

The role of innate immunity in cnidarian-dinoflagellate symbiosis

Creator:: Poole, Angela Z.
Abstract:: Cnidarians, such as corals and sea anemones serve as hosts to a variety of organisms including symbiotic dinoflagellates, bacteria, virus, and apicomplexans. As corals are vital to the health and productivity of the reef ecosystem it is important to understand how these organisms interact with each component of the holobiont....
Resource Type:: Dissertation
Full Text:: and teaching endeavors. I would also like to thank Eli Meyer, Michael Freitag, Mike Blouin, Kathy

The role of the transcriptional regulatory protein BCL11B in dental and craniofacial development

Creator:: Kyrylkova, Kateryna
Abstract:: BCL11B is a transcriptional regulatory protein that plays essential roles during mouse embryonic development. BCL11B is expressed and functions in the immune and nervous systems as well as within ectodermal organs. Multiple studies have characterized the roles of BCL11B in T cells, brain, and skin. However, very little is known...
Resource Type:: Dissertation
Full Text:: studies have characterized the roles of BCL11B in T cells, brain, and skin. However, very little is

Towards Resolving Functional and Evolutionary Mysteries of the Large and Heterozygous Genome of Hop (Humulus lupulus) and the Cannabaceae Family Using Genomic Data Science

Creator:: Padgitt-Cobb, Lillian K.
Abstract:: Hop (Humulus lupulus L. var. lupulus) is a diploid, dioecious plant with an extensive history of cultivation and use in brewing, as a textile, and for its therapeutic properties. Hop is prized for its ability to produce a variety of aromatic and flavor compounds, as well as compounds with anti-microbial...
Resource Type:: Dissertation
Full Text:: committee for their valuable guidance: Drs. David Hen- drix, John Henning, Michael Freitag, Maria Clara

Analyses of noncanonical DNA structures

Creator:: Khuu, Patricia A.
Abstract:: The structural polymorphic nature of DNA has been long been recognized since the model of the right-handed B-DNA duplex proposed by James Watson and Francis Crick was accepted. Its malleability is thought to be critical in protein recognition and manipulation. In particular, it can form Holliday junctions, four-way DNA structural...
Resource Type:: Dissertation
Full Text:: ....................................................................................... 37 3. A wobble A•T base pair in the structure of an asymmetric Holliday junction: Evidence for

Chlamydiae Enhance Self-Antigen Presentation in a Mechanism that is Dependent on Biosynthesis of Lipooligosaccharide

Creator:: Cram, Erik D.
Abstract:: Chlamydia is a genus of obligate intracellular bacteria that undergo a unique, biphasic developmental cycle. The infectious and metabolically inert Elementary Bodies (EBs) begin the cycle of infection by attaching and invading a host cells. Once inside, the EBs differentiate into the metabolically active, dividing Reticulate Bodies (RBs) within their...
Resource Type:: Dissertation
Full Text:: antigens, if present, to other cells such as CD8+ cytotoxic T cells. Previous research has identified

ScholarsArchive@OSU

Chemopreventative and chemotherapeutic properties of whole cruciferous vegetables and phytochemical components in acute T-cell lymphoblastic leukemia/lymphoma

In vivo detoxification of acetic acid in Saccharomyces cerevisiae

Perceptions on Spalted Wood: The Influence of Historic Spalting Patterns and Valuation of Spalted Wood Around the World.

Secondary Metabolism in Tolypocladium : Characterization, Ecology, Evolution and Regulation

Roles of homeodomain transcription factors during organogenesis

The role of innate immunity in cnidarian-dinoflagellate symbiosis

The role of the transcriptional regulatory protein BCL11B in dental and craniofacial development

Towards Resolving Functional and Evolutionary Mysteries of the Large and Heterozygous Genome of Hop (Humulus lupulus) and the Cannabaceae Family Using Genomic Data Science

Analyses of noncanonical DNA structures

Chlamydiae Enhance Self-Antigen Presentation in a Mechanism that is Dependent on Biosynthesis of Lipooligosaccharide

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