Index Catalog // ScholarsArchive@OSU

Towards Resolving Functional and Evolutionary Mysteries of the Large and Heterozygous Genome of Hop (Humulus lupulus) and the Cannabaceae Family Using Genomic Data Science

Creator:: Padgitt-Cobb, Lillian K.
Abstract:: Hop (Humulus lupulus L. var. lupulus) is a diploid, dioecious plant with an extensive history of cultivation and use in brewing, as a textile, and for its therapeutic properties. Hop is prized for its ability to produce a variety of aromatic and flavor compounds, as well as compounds with anti-microbial...
Resource Type:: Dissertation
Full Text:: : David A. Hendrix Hop (Humulus lupulus L. var. lupulus) is a diploid, dioecious plant with an exten

Investigating Local Energy Compensation of Adjacent RNA Secondary Structures in the bpRNA-1m Database

Creator:: Cornwell-Arquitt, Robert L.
Abstract:: Non-coding ribonucleic acid (ncRNA) is of interest for its diverse roles in cell and viral biology. RNA molecules vary greatly in terms of size, structure, and function. In recent years, the modification of existing RNA structures has been used for biochemical methods of enormous impact including CRISPR and RNAi methods....
Resource Type:: Honors College Thesis
Full Text:: and 5.4 kcal/mol (Figure 2C). In the aforementioned 6 figure, a group of high energy hairpins are

Genome-enabled discovery and characterization of type III effector-encoding genes of plant symbiotic bacteria

Creator:: Kimbrel, Jeffrey A.
Abstract:: Symbiosis is the close and protracted interaction between organisms. The molecular interactions that occur during symbiosis are complex with multiple barriers that must be overcome. Many Gram-negative, host-associated bacteria use a type III secretion system to mediate associations with their eukaryotic hosts. This secretion system is a specialized apparatus for...
Resource Type:: Dissertation
Full Text:: DISSERTATION OF Jeffrey A. Kimbrel for the degree of Doctor of Philosophy in Molecular and Cellular

Chlamydiae Enhance Self-Antigen Presentation in a Mechanism that is Dependent on Biosynthesis of Lipooligosaccharide

Creator:: Cram, Erik D.
Abstract:: Chlamydia is a genus of obligate intracellular bacteria that undergo a unique, biphasic developmental cycle. The infectious and metabolically inert Elementary Bodies (EBs) begin the cycle of infection by attaching and invading a host cells. Once inside, the EBs differentiate into the metabolically active, dividing Reticulate Bodies (RBs) within their...
Resource Type:: Dissertation
Full Text:: : Chlamydiae Enhance Self-Antigen Presentation in a Mechanism that is Dependent on Biosynthesis of

Secondary Metabolism in Tolypocladium : Characterization, Ecology, Evolution and Regulation

Creator:: Blount, Rheannon Rua
Abstract:: An increased understanding of secondary metabolism in fungi is important for both biological and societal reasons. The ascomycete genus, Tolypocladium, is an ideal system to explore secondary metabolism characterization, ecology, evolution and regulation. The genus produces and has the genomic potential to produce a wide array of metabolites. Paired with...
Resource Type:: Dissertation
Full Text:: produces and has the genomic potential to produce a wide array of metabolites. Paired with the ecological

Characterization of the pathogenicity and phylogeny of members of the Rhodococcus genus

Creator:: Creason, Allison L.
Abstract:: Plant pathogenic Rhodococcus species are persistent pathogens able to cause severe growth deformities on a large range of hosts. The most well studied species, R. fascians is predicted by current models to synthesize a mixture of cytokinins that act to directly perturb the hosts' hormone balances, which results in abnormal...
Resource Type:: Dissertation
Full Text:: growth deformities on a large range of hosts. The most well studied species, R. fascians is predicted

Transcriptomic analysis using high-throughput sequencing and DNA microarrays

Creator:: Fox, Samuel E.
Abstract:: Transcriptomics and gene expression profiling enables the elucidation of the genetic response of an organism to various environmental cues. Transcriptomics enables the deciphering of differences between two closely related organisms to the same environment and in contrast, enables the elucidation of genetic responses of the same organism to different environmental...
Resource Type:: Dissertation
Full Text:: relatively new and protocols must be developed for the analyses of transcriptomes (RNA- sequencing). A RNA

Regulation of the Pantoea agglomerans type III secretion system by plant-exuded sugars

Creator:: Bacher, Daniel
Abstract:: Pantoea agglomerans pathovar betae (Pab) is a bacterium that causes galls on the roots of beet plants, resulting in reduced marketability of beet roots and crop loss. Pab uses a type III secretion system (T3SS) to infect and cause galls on beets. The T3SS is a molecular syringe-like structure that...
Resource Type:: Honors College Thesis
Full Text:: sufficient resolution on a gel between the cut and uncut versions of the plasmid (Figure 2C). Gibson

Developmental toxicity of polycyclic aromatic hydrocarbons : defining mechanisms with systems-based transcriptional profiling

Creator:: Goodale, Britton C.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous in the environment as components of fossil fuels and by-products of combustion. Defining toxicity mechanisms for this large family of multi-ring structures and substituted derivatives is a substantial challenge. Several PAHs, such as benzo(a)pyrene (BaP), are mutagenic, toxic to wildlife, and classified as probable...
Resource Type:: Dissertation
Full Text:: this large family of multi-ring structures and substituted derivatives is a substantial challenge

In vivo detoxification of acetic acid in Saccharomyces cerevisiae

Creator:: Ding, Jun
Abstract:: The studies described in this thesis were motivated by ongoing efforts to develop lignocellulosic biomass as an efficient and practical source of renewable energy. Enormous problems complicate these efforts to reduce reliance on greenhouse gas-generating fossil fuels. Simply obtaining the fermentable sugars available in the cellulose and hemicellulose components of...
Resource Type:: Dissertation
Full Text:: . S. cerevisiae has a long and rich history of use in food and beverage production, e.g., baking

ScholarsArchive@OSU

Towards Resolving Functional and Evolutionary Mysteries of the Large and Heterozygous Genome of Hop (Humulus lupulus) and the Cannabaceae Family Using Genomic Data Science

Investigating Local Energy Compensation of Adjacent RNA Secondary Structures in the bpRNA-1m Database

Genome-enabled discovery and characterization of type III effector-encoding genes of plant symbiotic bacteria

Chlamydiae Enhance Self-Antigen Presentation in a Mechanism that is Dependent on Biosynthesis of Lipooligosaccharide

Secondary Metabolism in Tolypocladium : Characterization, Ecology, Evolution and Regulation

Characterization of the pathogenicity and phylogeny of members of the Rhodococcus genus

Transcriptomic analysis using high-throughput sequencing and DNA microarrays

Regulation of the Pantoea agglomerans type III secretion system by plant-exuded sugars

Developmental toxicity of polycyclic aromatic hydrocarbons : defining mechanisms with systems-based transcriptional profiling

In vivo detoxification of acetic acid in Saccharomyces cerevisiae

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