Index Catalog // ScholarsArchive@OSU

Roles of homeodomain transcription factors during organogenesis

Creator:: Xu, Jun
Abstract:: The spatial and temporal patterning of sequence specific transcription factors (SSTFs) contributes to cell type specification and organ formation during embryogenesis. Homeodomain transcription factors are evolutionally conserved among invertebrate and vertebrate animals. They are responsible for body segmentation and organogenesis. Lbx1 and Pitx2 both are homeodomain transcription factors contributing to...
Resource Type:: Dissertation
Full Text:: FIGURES (CONTINUED) Figure 4-4. RNA Expression Pattern of A Cluster and D Cluster Hox Genes

Analyses of noncanonical DNA structures

Creator:: Khuu, Patricia A.
Abstract:: The structural polymorphic nature of DNA has been long been recognized since the model of the right-handed B-DNA duplex proposed by James Watson and Francis Crick was accepted. Its malleability is thought to be critical in protein recognition and manipulation. In particular, it can form Holliday junctions, four-way DNA structural...
Resource Type:: Dissertation
Full Text:: lab and Ortiz-Lombardı´ et al. (Ortiz-Lombardia et al. 1999; Eichman et al. 2000). Two stacked-X

The role of the transcriptional regulatory protein BCL11B in dental and craniofacial development

Creator:: Kyrylkova, Kateryna
Abstract:: BCL11B is a transcriptional regulatory protein that plays essential roles during mouse embryonic development. BCL11B is expressed and functions in the immune and nervous systems as well as within ectodermal organs. Multiple studies have characterized the roles of BCL11B in T cells, brain, and skin. However, very little is known...
Resource Type:: Dissertation
Full Text:: basal ganglia disorders. Trends Neurosci 12, 366-75. Albu, D. I., Feng, D., Bhattacharya, D., Jenkins

Perceptions on Spalted Wood: The Influence of Historic Spalting Patterns and Valuation of Spalted Wood Around the World.

Creator:: Vega Gutiérrez, Patricia T.
Abstract:: During the 1400s – 1600s, spalted wood was an expensive commodity used in marquetry style artworks across primarily Germany and Italy. It fell out of favor during the Industrial Revolution, but is currently experiencing resurgence in popularity with US woodturners. How spalted wood is used, and what types of spalted...
Resource Type:: Dissertation
Full Text:: ............................................................................ 95 c) Sample dying process ................................................................ 96 d

Classifying Chemical Bioactivity by Coupling High-throughput Phenotypic Anchoring and Transcriptome Profiling in Zebrafish

Creator:: Haggard, Derik
Abstract:: There are more than 87,000 chemicals in current use with little to no toxicity information available. Assessing such a large number of chemicals using traditional methods would take an unreasonable amount of time and money, and require the use a large number of animals. The incorporation of high-throughput in vivo...
Resource Type:: Dissertation
Full Text:: (e.g. estrogen, androgen, vitamin D, and thyroid hormone receptors) (Huang et al., 2014b; Huang et al

Characterization of the pathogenicity and phylogeny of members of the Rhodococcus genus

Creator:: Creason, Allison L.
Abstract:: Plant pathogenic Rhodococcus species are persistent pathogens able to cause severe growth deformities on a large range of hosts. The most well studied species, R. fascians is predicted by current models to synthesize a mixture of cytokinins that act to directly perturb the hosts' hormone balances, which results in abnormal...
Resource Type:: Dissertation

Investigating Transcriptional Control of Specialized Gene Expression in Plants

Creator:: Fraser, Valerie N.
Abstract:: Specialized or secondary metabolism is a collection of pathways and small molecules that, while beneficial to an organism, are not strictly necessary for survival. Plants use secondary metabolites to, among other things, attract pollinators, defend against biotic and abiotic stressors, and form symbioses. Natural products from plants have seen an...
Resource Type:: Dissertation

Biophysical basis of macromolecular assembly in the dynein cargo attachment complex

Creator:: Hall, Justin Daniel
Abstract:: Cytoplasmic dynein is an ATP-dependent, microtubule-based molecular motor involved in the positioning and trafficking of cellular cargo. The cargo binding sub-domain of dynein contains the natively disordered intermediate chain (IC) and the homodimeric light chains (Tctex1, LC8 and LC7). The structure and stoichiometry of this complex, how the light chains...
Resource Type:: Dissertation
Full Text:: ........................................................................................... 42 2.11 Comparison of H/D and H/H exchange between LC8 dimer and H55K monomer

Towards Resolving Functional and Evolutionary Mysteries of the Large and Heterozygous Genome of Hop (Humulus lupulus) and the Cannabaceae Family Using Genomic Data Science

Creator:: Padgitt-Cobb, Lillian K.
Abstract:: Hop (Humulus lupulus L. var. lupulus) is a diploid, dioecious plant with an extensive history of cultivation and use in brewing, as a textile, and for its therapeutic properties. Hop is prized for its ability to produce a variety of aromatic and flavor compounds, as well as compounds with anti-microbial...
Resource Type:: Dissertation

Secondary Metabolism in Tolypocladium : Characterization, Ecology, Evolution and Regulation

Creator:: Blount, Rheannon Rua
Abstract:: An increased understanding of secondary metabolism in fungi is important for both biological and societal reasons. The ascomycete genus, Tolypocladium, is an ideal system to explore secondary metabolism characterization, ecology, evolution and regulation. The genus produces and has the genomic potential to produce a wide array of metabolites. Paired with...
Resource Type:: Dissertation
Full Text:: circumventing host immune systems and defenses (Ortiz-Urquiza and Keyhani, 2013; Quandt et al., 2018

ScholarsArchive@OSU

Roles of homeodomain transcription factors during organogenesis

Analyses of noncanonical DNA structures

The role of the transcriptional regulatory protein BCL11B in dental and craniofacial development

Perceptions on Spalted Wood: The Influence of Historic Spalting Patterns and Valuation of Spalted Wood Around the World.

Classifying Chemical Bioactivity by Coupling High-throughput Phenotypic Anchoring and Transcriptome Profiling in Zebrafish

Characterization of the pathogenicity and phylogeny of members of the Rhodococcus genus

Investigating Transcriptional Control of Specialized Gene Expression in Plants

Biophysical basis of macromolecular assembly in the dynein cargo attachment complex

Towards Resolving Functional and Evolutionary Mysteries of the Large and Heterozygous Genome of Hop (Humulus lupulus) and the Cannabaceae Family Using Genomic Data Science

Secondary Metabolism in Tolypocladium : Characterization, Ecology, Evolution and Regulation

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