Index Catalog // ScholarsArchive@OSU

Genome-enabled discovery and characterization of type III effector-encoding genes of plant symbiotic bacteria

Creator:: Kimbrel, Jeffrey A.
Abstract:: Symbiosis is the close and protracted interaction between organisms. The molecular interactions that occur during symbiosis are complex with multiple barriers that must be overcome. Many Gram-negative, host-associated bacteria use a type III secretion system to mediate associations with their eukaryotic hosts. This secretion system is a specialized apparatus for...
Resource Type:: Dissertation
Full Text:: fellow graduate students, particularly Sam Fox and Bill Thomas, who made the lows seem a little higher

Investigating Transcriptional Control of Specialized Gene Expression in Plants

Creator:: Fraser, Valerie N.
Abstract:: Specialized or secondary metabolism is a collection of pathways and small molecules that, while beneficial to an organism, are not strictly necessary for survival. Plants use secondary metabolites to, among other things, attract pollinators, defend against biotic and abiotic stressors, and form symbioses. Natural products from plants have seen an...
Resource Type:: Dissertation
Full Text:: , 2021. Title: Investigating Transcriptional Control of Specialized Gene Expression in Plants

Growth, morphology, and in vitro development of transgenic poplars with RNAi-inhibited PtDDM1-1/2 gene expression

Creator:: Zhu, Ruoqing
Abstract:: Epigenetic mechanisms are important for control of plant development, and may play a particularly important role in trees given their long life cycles and distinctive and stable tissue types. To help understand the role of epigenetics in tree development, we produced transgenic poplars with reduced activity of the DDM1 genes,...
Resource Type:: Masters Thesis
Full Text:: : Growth, Morphology, and in Vitro Development of Transgenic Poplars with RNAi-inhibited PtDDM1-1/2 Gene

Transcriptional regulation of the human cathelicidin antimicrobial peptide gene

Creator:: Guo, Chunxiao
Abstract:: Human cathelicidin antimicrobial peptide (CAMP/LL-37) is a cationic antimicrobial peptide that is widely expressed by myeloid and epithelial cells at the human-environment interface. It possesses broad spectrum antimicrobial capacity against bacteria, fungi and viruses. In addition to its direct antimicrobial activity, CAMP/LL-37 also attracts and recruits monocytes, neutrophils and other...
Resource Type:: Dissertation
Full Text:: Antimicrobial Peptide Gene

Antimicrobial peptide regulation by small molecules in humans and other primates

Creator:: Sinnott, Brian D.
Abstract:: Antimicrobial peptides (AMPs) play an important role in the innate immune system. Determining the pathways by which these proteins are regulated allows for modulation of their expression for better health. Two families of antimicrobial peptides have been studied in humans: cathelicidins and defensins. There is a single cathelicidin in humans...
Resource Type:: Masters Thesis
Full Text:: defenses and health. The human cathelicidin antimicrobial peptide gene is regulated by a

Effects of DNA mismatch repair inhibition in Arabidopsis thaliana

Creator:: Wilcox, Buck W. L.
Abstract:: Genomic instability underlies diseases of unregulated cell growth that result in cancers and developmental abnormalities in humans. Similar genome destabilizing mechanisms are used to create genetic variety in crops for use in breeding and trait development. Errors that occur during DNA replication may cause mutations if they are not corrected...
Resource Type:: Dissertation
Full Text:: somatic mutations, or they require insertion of a different reporter gene construct into the plants

Chlamydiae Enhance Self-Antigen Presentation in a Mechanism that is Dependent on Biosynthesis of Lipooligosaccharide

Creator:: Cram, Erik D.
Abstract:: Chlamydia is a genus of obligate intracellular bacteria that undergo a unique, biphasic developmental cycle. The infectious and metabolically inert Elementary Bodies (EBs) begin the cycle of infection by attaching and invading a host cells. Once inside, the EBs differentiate into the metabolically active, dividing Reticulate Bodies (RBs) within their...
Resource Type:: Dissertation
Full Text:: many of the chlamydial strains used in this work. My committee members, Thomas J. Wolpert, Michael

Towards Resolving Functional and Evolutionary Mysteries of the Large and Heterozygous Genome of Hop (Humulus lupulus) and the Cannabaceae Family Using Genomic Data Science

Creator:: Padgitt-Cobb, Lillian K.
Abstract:: Hop (Humulus lupulus L. var. lupulus) is a diploid, dioecious plant with an extensive history of cultivation and use in brewing, as a textile, and for its therapeutic properties. Hop is prized for its ability to produce a variety of aromatic and flavor compounds, as well as compounds with anti-microbial...
Resource Type:: Dissertation
Full Text:: sufficiently capture the surrounding genomic context of genes, including transposable elements and gene

Characterization of the pathogenicity and phylogeny of members of the Rhodococcus genus

Creator:: Creason, Allison L.
Abstract:: Plant pathogenic Rhodococcus species are persistent pathogens able to cause severe growth deformities on a large range of hosts. The most well studied species, R. fascians is predicted by current models to synthesize a mixture of cytokinins that act to directly perturb the hosts' hormone balances, which results in abnormal...
Resource Type:: Dissertation
Full Text:: been attributed to proteins encoded by the fas locus. The fasD gene encodes an isopentenyl

Transcriptomic analysis using high-throughput sequencing and DNA microarrays

Creator:: Fox, Samuel E.
Abstract:: Transcriptomics and gene expression profiling enables the elucidation of the genetic response of an organism to various environmental cues. Transcriptomics enables the deciphering of differences between two closely related organisms to the same environment and in contrast, enables the elucidation of genetic responses of the same organism to different environmental...
Resource Type:: Dissertation
Full Text:: microarrays. Abstract approved: Todd C. Mockler Transcriptomics and gene expression

ScholarsArchive@OSU

Genome-enabled discovery and characterization of type III effector-encoding genes of plant symbiotic bacteria

Investigating Transcriptional Control of Specialized Gene Expression in Plants

Growth, morphology, and in vitro development of transgenic poplars with RNAi-inhibited PtDDM1-1/2 gene expression

Transcriptional regulation of the human cathelicidin antimicrobial peptide gene

Antimicrobial peptide regulation by small molecules in humans and other primates

Effects of DNA mismatch repair inhibition in Arabidopsis thaliana

Chlamydiae Enhance Self-Antigen Presentation in a Mechanism that is Dependent on Biosynthesis of Lipooligosaccharide

Towards Resolving Functional and Evolutionary Mysteries of the Large and Heterozygous Genome of Hop (Humulus lupulus) and the Cannabaceae Family Using Genomic Data Science

Characterization of the pathogenicity and phylogeny of members of the Rhodococcus genus

Transcriptomic analysis using high-throughput sequencing and DNA microarrays

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