Search Constraints

Start Over
Filtering by: Creator Turner, Brenda Remove constraint Creator: Turner, Brenda Committee Member Freitag, Michael Remove constraint Committee Member: Freitag, Michael

Search Results

  • Antimicrobial peptide regulation by small molecules in humans and other primates

    Creator:
    Sinnott, Brian D.
    Abstract:
    Antimicrobial peptides (AMPs) play an important role in the innate immune system. Determining the pathways by which these proteins are regulated allows for modulation of their expression for better health. Two families of antimicrobial peptides have been studied in humans: cathelicidins and defensins. There is a single cathelicidin in humans...
    Resource Type:
    Masters Thesis
    Full Text:
    immune system. Secondly I’d like to thank Jing Chen and Brenda Nui. Both undergraduates have shown a

  • Transcriptional regulation of the human cathelicidin antimicrobial peptide gene

    Creator:
    Guo, Chunxiao
    Abstract:
    Human cathelicidin antimicrobial peptide (CAMP/LL-37) is a cationic antimicrobial peptide that is widely expressed by myeloid and epithelial cells at the human-environment interface. It possesses broad spectrum antimicrobial capacity against bacteria, fungi and viruses. In addition to its direct antimicrobial activity, CAMP/LL-37 also attracts and recruits monocytes, neutrophils and other...
    Resource Type:
    Dissertation
    Full Text:
    described in Chapter 3. Brian Sinnott and Brenda Niu designed and carried out the chemical library