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Filtering by: Creator Watson, Sawyer Committee Member Fu, Elain Degree Level Doctoral

Characterization of Mycobacterium avium subsp. hominissuis Interactions with Host Macrophages and Multinucleated Giant Cells

Creator:

Joseph, Jayanthi J.

Abstract:

To examine the macrophage response to M. avium, I compared inflammasome and cytosolic sensor expression and activation. My result demonstrated that virulent strains of M. avium (A5 and 104) suppress IL-1β production and induce IFN-β production in macrophages. M. avium mutants deficient at DNA export in the biofilm exhibited reduced...

Resource Type:

Dissertation

Full Text:

type I interferons (IFN-α and IFN-β) (Schoggins et al., 2014; Watson et al., 2015). Cytosolic DNA
Comprehensive, Low-Cost Wicking Microfluidic Analytical Devices for Clinical Diagnostics and Environmental Analysis

Creator:

Bandara, Gayan C.

Abstract:

Analytical techniques are utilized in a wide variety of applications. Traditionally, analytical measurements are achieved by trained personnel in a laboratory setting using expensive scientific instruments, which limits their applicability in resource-limited areas and point-of-care applications. Therefore, the concept of enabling these laboratory-based qualitative and quantitative assays in microfluidic device...

Resource Type:

Dissertation

Full Text:

like to thank Teresa Sawyer and Dr. Peter Eschbach for their training and assistance with