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Filtering by: Creator Demessie, E. Sahle Remove constraint Creator: Demessie, E. Sahle Committee Member Gable, Kevin Remove constraint Committee Member: Gable, Kevin License All rights reserved Remove constraint License: All rights reserved

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  • Exploring Pactamycin Biosynthesis

    Creator:
    Roland, Jessica
    Abstract:
    Pactamycin, produced by the soil bacterium Streptomyces pactum, is a cytotoxic antibiotic that belongs to the aminocyclitol family of natural products. This antibiotic has shown various forms of biological activity, including antibacterial, antifungal, antimalarial, and antitumor activities. Despite its outstanding biological activity, the mode of formation of its pharmacophore (the...
    Resource Type:
    Honors College Thesis
    Full Text:
    into Escherichia coli BL21 pLysS. SDS-PAGE gel electrophoresis showed that the transformed E. coli