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Filtering by: Committee Member Bailey, George Committee Member Gamble, Wilbert

Modulation of chemically-induced hepatocarcinogenesis by indole-3-carbinol : mechanisms and species comparison

Creator:

Oganesian, Aram

Abstract:

There is plenty of evidence from epidemiology studies supporting a link between certain components in the human diet and cancer incidence. It is estimated that 3-4 million annual cases of cancer could be prevented worldwide just by changing dietary habits. In parts of the world where vegetables and fruits constitute...

Resource Type:

Dissertation

Full Text:

contribution in sampling my carcinogenesis experiments. I was fortunate to have Drs. George Bailey, Donald
Indole-3-carbinol and 3,3'-diindolylmethane : relative potency as modulators of drug metabolism and carcinogenesis

Creator:

Katchamart, Sirinmas

Abstract:

Indole-3-carbinol (I3C), the most abundant metabolite of glucobrassicins, is found in cruciferous vegetables such as broccoli, Brussels sprouts, cabbage and cauliflower. I3C has been shown to have anticarcinogenic activity against many chemical carcinogens in multiple target organs in animal models. However, the anticarcinogenic activity of I3C is considered indirect since...

Resource Type:

Dissertation

Full Text:

and financial support. Thanks to Drs. Donald Reed, George Bailey, Mark Christensen and Wilbert Gamble