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Filtering by: Creator Baker, C. Scott Committee Member Gitelman, Alix Committee Member Proteau, Rosita

1) Preparation of Acetaminophen Capsules Containing Beads Prepared by Hot-melt Direct Blend Coating Method 2) Pharmacokinetic Modeling and Monte Carlo Simulations in The Context of Additional Criteria for Bioequivalence Assessments 3) Pharmacokinetic Prediction of Levofloxacin Accumulation in Tissue and its Association to Tendinopathy

Creator:

Pham, Loan

Abstract:

The thrust of this thesis is to study oral solid dosage formulation using hot melt coating method and to use pharmacokinetic modeling and simulation (PK M&S) as a tool that can help to predict pharmacokinetics of a drug in human and the probability of passing various bioequivalence criteria of the...

Resource Type:

Dissertation

Full Text:

, and Cmax) plus AUC0-1 (a), AUC0-2 (b), AUC0-3 (c), AUC0-4(d). ........ 100 Figure 35: Probability of
Development of novel spray coated soft elastic gelatin capsule sustained release formulations of nifedipine, bioavailability and bioequivalence of verapamil HCL controlled release formulations, pharmacokinetics of terbinafine after single oral doses in raptors

Creator:

Fahmy, Sahar Abd El-Sattar

Abstract:

This dissertation describes the development of a new sustained release formulation of nifedipine. The new formulation was developed by coating commercially available immediate release soft elastic gelatin capsules using a spray coating technique with two different polymeric combinations. Dissolution studies were conducted and showed that controlled release of nifedipine was...

Resource Type:

Dissertation

Full Text:

, pellets, or granules. c) Osmotically driven systems. 7 d) Systems controlled by ion exchange

ScholarsArchive@OSU

Development of novel spray coated soft elastic gelatin capsule sustained release formulations of nifedipine, bioavailability and bioequivalence of verapamil HCL controlled release formulations, pharmacokinetics of terbinafine after single oral doses in raptors

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