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Filtering by: Subject Time-of-flight mass spectrometry Remove constraint Subject: Time-of-flight mass spectrometry Committee Member Hagen, Tory M. Remove constraint Committee Member: Hagen, Tory M. Degree Level Doctoral Remove constraint Degree Level: Doctoral

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  • Development and broad application of a mass spectrometry based metabolomics platform

    Creator:
    Kirkwood, Jay Steven
    Abstract:
    Metabolomics is a comprehensive analysis of small molecules, or metabolites, in a system. Metabolomics is a hypothesis-generating experiment and offers an unbiased analysis of cell metabolism that can aid in the understanding of fundamental biological processes. Metabolomics is widely and broadly applicable in the biological sciences and has been used...
    Resource Type:
    Dissertation
    Full Text:
    chromatography-quadrupole-time-of-flight mass spectrometry metabolomics platform and details the various steps

  • Chemical labeling methods and mass spectrometry of mitochondrial thiol proteomes

    Creator:
    Wang, Jing
    Abstract:
    Dysfunction of mitochondria has been linked to aging and the pathogenesis of many degenerative diseases. Aside from their primary function in energy production, mitochondria are considered as a major source and target of reactive oxygen and nitrogen species (ROS/RNS) in cells as well. The mitochondrial thiol proteome is a subset...
    Resource Type:
    Dissertation
    Full Text:
    commonly used mass analyzers in this field include the quadrupole (Q), ion trap (IT), time-of-flight (TOF