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Filtering by: Subject Microsomes -- Effect of chemicals on Remove constraint Subject: Microsomes -- Effect of chemicals on Committee Member Harding, Anna Remove constraint Committee Member: Harding, Anna

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  • Developmental axial skeletal deformities : baseline study with a zebrafish model

    Creator:
    Harden, Jon M.
    Abstract:
    The aim of this study was to assess sensitivity of early life stage zebrafish to cadmium (Cd). Embryos and larva were exposed to Cd before the formation of skeletal elements. Exposure times were selected to determine whether Cd perturbed developmental processes that lead to skeletal deformities, and to characterize the...
    Resource Type:
    Masters Thesis
    Full Text:
    . There was no effect of Cd on incidence of any type of skeletal deformity at 4Odpf(P>O.05 and p>O.O5

  • In Utero Exposure to Arsenic and Mercury : Epigenome-Wide Associations and Newborn Health Outcomes

    Creator:
    Cardenas, Andres
    Abstract:
    Mercury and arsenic are known developmental toxicants and environmental exposures are ubiquitous worldwide from natural and anthropogenic sources. Prenatal exposure to both contaminants are independently associated with adverse perinatal health outcomes and latent disease risk that could be in part mediated by epigenetic reprogramming events. Fetal programming events involving DNA...
    Resource Type:
    Dissertation
    Full Text:
    methylation in different biological human tissues. Particularly, the effect of arsenic exposure on