Search Constraints

Start Over
Filtering by: Subject Zebra danio -- Genetics Remove constraint Subject: Zebra danio -- Genetics Committee Member Harding, Anna Remove constraint Committee Member: Harding, Anna

Search Results

  • Consequences of miRNA misregulation on embryonic development and aging

    Creator:
    Franzosa, Jill A.
    Abstract:
    microRNAs (miRNAs), ~21-24 nucleotide-long RNAs that post-transcriptionally regulate gene expression, have rapidly become one of the most extensively studied mechanisms of the past decade. Since their discovery as temporal regulators of post-embryonic development in C. elegans, miRNAs have been functionally implicated in almost every cellular process investigated to date. miRNAs...
    Resource Type:
    Dissertation
    Full Text:
    the many genetic and biochemical processes which contribute to stem cell aging (i.e. telomerase

  • Developmental axial skeletal deformities : baseline study with a zebrafish model

    Creator:
    Harden, Jon M.
    Abstract:
    The aim of this study was to assess sensitivity of early life stage zebrafish to cadmium (Cd). Embryos and larva were exposed to Cd before the formation of skeletal elements. Exposure times were selected to determine whether Cd perturbed developmental processes that lead to skeletal deformities, and to characterize the...
    Resource Type:
    Masters Thesis
    Full Text:
    Chapter 2 Materials and Methods Embryos of the zebrafish Danio (Brachyodanio) rerio TL line were obtained

  • In vivo assessment of nanomaterial-induced toxicity using embryonic zebrafish

    Creator:
    Usenko, Crystal Y.
    Abstract:
    Due to their unique physical, chemical, and magnetic properties, nanomaterials have great potential for industrial development. There is a pressing need to develop rapid whole animal-based testing assays to assess the potential toxicity of engineered nanomaterials. To meet this challenge the embryonic zebrafish model was employed to determine the toxicity...
    Resource Type:
    Masters Thesis
    Full Text:
    Potential of Fullerenes……………… 36 Genetic Reduction of GSH………………………… 37 Lipid Peroxidation Detection