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Filtering by: Creator Huynh, Cuong Van Committee Member Heidel, Jerry

Investigating the basis of substrate specificity in butane monooxygenase and chlorinated ethene toxicity in Pseudomonas butanovora

Creator:

Halsey, Kimberly H.

Abstract:

Pseudomonas butanovora, Mycobacterium vaccae, and Nocardioides sp. CF8 utilize distinctly different butane monooxygenases (BMOs) to initiate degradation of recalcitrant chlorinated ethenes (CEs) that pollute aquifers and soils. BMO-dependent degradation of CEs such as trichloroethylene (TCE) can lead to cellular toxicities. The type and severity of TCE transformation-dependent damage can have...

Resource Type:

Dissertation

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serves as a useful methane- surrogate because its van der Waals radius is about the same as methane
Hemoglobin adducts of the organophosphate insecticide azinphos-methyl

Creator:

Bailey, Bonnie J.

Abstract:

Reported here is an investigation to determine if azinphos-methyl (AZM), an organophosphate insecticide, adducts to hemoglobin, and if so, whether the hemoglobin adduct could be used as a quantitative marker of occupational AZM exposure. We hypothesized that AZM, or a metabolite of AZM, binds to hemoglobin in erythrocytes forming an...

Resource Type:

Dissertation

Full Text:

blood proteins (Van Welie et al., 1992). Researchers found hemoglobin possessed many of the qualities
Surface-exposed proteins in the pathogenesis of Mycobacterium avium subsp. hominissuis

Creator:

McNamara, Michael J.

Abstract:

Mycobacterium avium subsp. hominissuis (MAH) is a pervasive environmental bacterium that can cause opportunistic infections in humans. Among the most robust and hardy members of the Mycobacterium genus, M. avium can persist and thrive in a range of challenging environments, including many which place it in direct contact with humans....

Resource Type:

Dissertation