Index Catalog // ScholarsArchive@OSU

Structural and functional analysis of the 57 kDa protein produced by the fish pathogen, Renibacterium salmoninarum

Creator:: Wiens, Gregory D.
Abstract:: Little is known about the virulence factors of Renibacterium salmoninarum, the causative agent of salmonid bacterial kidney disease. The predominant protein produced by R. salmoninarum in broth culture or during infection is a 57/58 kDa protein (p57) which is associated with strain virulence. In this study monoclonal antibodies (MAbs) to...
Resource Type:: Dissertation
Full Text:: the major component and found to be heat stable (100°C for 0.5 h). Cross absorption experiments with

Characterization of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced modification of hepatic pyruvate carboxylase gene expression in C57BL/6J male mice

Creator:: Sparrow, Barney R.
Abstract:: The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure on hepatic pyruvate carboxylase (PC) gene expression were investigated in C57BL/6J Ah[superscipt b/b male mice. A dose-dependent reduction of PC levels and activity occurred in animals given a single intraperitoneal dose of TCDD in a corn oil carrier. The dose ranged from 1 to...
Resource Type:: Dissertation

Non-specific innate immunity against Escherichia coli infection in white leghorn chickens

Creator:: Huang, Hsuan-Jen
Abstract:: This research was initiated to investigate a high mortality problem occurring in market age broiler chickens in Oregon. Initial field investigations revealed that mortality was due to the systemic bacterial infections. The subsequent laboratory experiments suggested that suppressed short-term, non-specific innate immunity rather than pathogenic properties of bacteria caused the...
Resource Type:: Dissertation
Full Text:: 24 hrs after the intra-airsac inoculation; F, fresh; 0, old; F + H, heated fresh vaccine; AC

Hemoglobin adducts of the organophosphate insecticide azinphos-methyl

Creator:: Bailey, Bonnie J.
Abstract:: Reported here is an investigation to determine if azinphos-methyl (AZM), an organophosphate insecticide, adducts to hemoglobin, and if so, whether the hemoglobin adduct could be used as a quantitative marker of occupational AZM exposure. We hypothesized that AZM, or a metabolite of AZM, binds to hemoglobin in erythrocytes forming an...
Resource Type:: Dissertation
Full Text:: members of my committee: Jeff Jenkins, Max Deinzer, Sheldon Wagner, Nancy Kerkvliet, and Jerry Heidel for

Involvement of inflammation and associated Mac-1⁺Gr-1⁺ cells in the immune suppression induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

Creator:: Choi, Jin-Young, 1964
Abstract:: Exposure to TCDD suppresses the generation of immune responses through unknown mechanisms. Interestingly, TCDD enhances inflammatory responses to various stimuli. The goal of the studies presented in this thesis was to examine the role of hyperinflammation in TCDD-induced immunotoxicity. Previously we observed an increase in Mac-1⁺ cells in the spleen...
Resource Type:: Dissertation

Genetic variation of chlamydial Inc proteins

Creator:: Viratyosin, Wasna
Abstract:: Genomic analysis is a new approach for the characterization and investigation of novel genes, gene clusters, the function of uncharacterized proteins, and genetic diversity in microorganisms. These approaches are important for the study of chlamydiae, a system in which several genomes have been sequenced but in which techniques for genetic...
Resource Type:: Dissertation
Full Text:: : B class (B, Ba, D, Da, E, Li, L2 and L2a), C class (A, C, H, I, Ta, J, Ja, K and L3), and

Impacts of multispecies parasitism on coho salmon (Oncorhynchus kisutch) in Oregon

Creator:: Ferguson, Jayde A.
Abstract:: Diseases caused by parasites are recognized as significant sources of mortality in wild fish populations. I assessed the impacts of multispecies parasitism on a threatened stock of juvenile coho salmon (Oncorhynchus kisutch). A crucial prerequisite to this research was proper identification of parasites, which can be difficult for species lacking...
Resource Type:: Dissertation
Full Text:: . ................................................................................................... 157 Figure 5.2. Histological sections (H&E) of muscle parasites in coho salmon (Oncorhynchus

Functional, structural and evolutionary analyses of the ferritin-like superfamily of proteins

Creator:: Cooley, Richard Bleier
Abstract:: The ferritin-like superfamily (FLSF) of proteins is composed of a wide variety of functionally diverse proteins involved in oxygen dependent metal-mediated electron transfer reactions. Their biological importance is exemplified by the fact FLSF proteins are found in almost every organism from all three domains of life. Their functions range from...
Resource Type:: Dissertation
Full Text:: unreactive C-H bond. Rubrerythrins, on the other hand, are peroxidases most commonly found in anaerobic

A comparative study of fish coloration and toxicant responses in a chromatophore cell-based biosensor

Creator:: Roach, Holly B.
Abstract:: Detection of both biological and chemical environmental toxicants is essential in the assessment of risk to human health. Cell-based biosensors are capable of activity- based detection of toxicity. Chromatophore cells, responsible for the pigmentation of poikilothermic animal, have shown immense potential as cell-based biosensors in the detection of a broad...
Resource Type:: Masters Thesis

Surface-exposed proteins in the pathogenesis of Mycobacterium avium subsp. hominissuis

Creator:: McNamara, Michael J.
Abstract:: Mycobacterium avium subsp. hominissuis (MAH) is a pervasive environmental bacterium that can cause opportunistic infections in humans. Among the most robust and hardy members of the Mycobacterium genus, M. avium can persist and thrive in a range of challenging environments, including many which place it in direct contact with humans....
Resource Type:: Dissertation
Full Text:: undergraduates include: Alex Nguyen, Chris Moser, Mukhdip Singh, Jeff Wagner and Ian Hilgart. It is also

ScholarsArchive@OSU

Structural and functional analysis of the 57 kDa protein produced by the fish pathogen, Renibacterium salmoninarum

Characterization of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced modification of hepatic pyruvate carboxylase gene expression in C57BL/6J male mice

Non-specific innate immunity against Escherichia coli infection in white leghorn chickens

Hemoglobin adducts of the organophosphate insecticide azinphos-methyl

Involvement of inflammation and associated Mac-1⁺Gr-1⁺ cells in the immune suppression induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

Genetic variation of chlamydial Inc proteins

Impacts of multispecies parasitism on coho salmon (Oncorhynchus kisutch) in Oregon

Functional, structural and evolutionary analyses of the ferritin-like superfamily of proteins

A comparative study of fish coloration and toxicant responses in a chromatophore cell-based biosensor

Surface-exposed proteins in the pathogenesis of Mycobacterium avium subsp. hominissuis

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