Index Catalog // ScholarsArchive@OSU

Machine learning approach to improve drug discovery in natural product extracts

Creator:: Heussner, Robert T.
Abstract:: Current natural product (NP) research is limited by its reliance on bioassay-guided fractionation to identify bioactive compounds in mixtures. Computational approaches may improve NP research by correlating mass spectra (MS) and nuclear magnetic resonance spectra (NMR) of bioactive mixtures to their bioactivity patterns. In this study, I use artificial neural...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Adam Higgins, Committee Member, representing Chemical, Biological, and Environmental

Ink and Substrate Compatibility for Electrochemical Sensing in Paper-based Devices

Creator:: Reid, Caitlin A.
Abstract:: Electrochemical sensing provides a quantitative alternative to colorimetric reactions within paper-based devices. The paper-based devices were fabricated by screen printing the conductive and reference inks onto porous substrates that were evaluated using cyclic voltammetry. Devices were evaluated based on the magnitude of the average anodic peak height, which correlates with...
Resource Type:: Honors College Thesis
Full Text:: Engineering _____________________________________________________________________ Adam Higgins

Oxidation of Amorphous Metal Alloy Surfaces Studied Using Ambient Pressure X-Ray Photoelectron Spectroscopy

Creator:: Alzaga Elizondo, Pedro
Abstract:: Amorphous metal thin films (AMTFs) are of growing interest due to their unique mechanical properties and chemical stability. AMTFs have an advantage over polycrystalline metal films due to the lack of grain boundaries which gives AMTFs added durability and relatively smoother surfaces. For this reason, AMTFs have been investigated as...
Resource Type:: Masters Thesis
Full Text:: Abstract approved: _______________________________________________________________ Gregory S. Herman

Optimal control of an underactuated bipedal robot

Creator:: Jones, Mikhail S.
Abstract:: Bipedal robots represent a unique class of control problems that combine many of the most difficult elements of nonlinear control. These robots are typically designed to be mobile and as such have limited energy and actuator authority making efficiency a prime concern. Unlike wheeled robots, legged robots must transition between...
Resource Type:: Masters Thesis
Full Text:: ABSTRACT OF THE THESIS OF Mikhail S. Jones for the degree of Master of Science in Mechanical Engineering

Modelling Thin Liquid Film Draining of Bubbles on Porous Media in Confined Geometry

Creator:: Bahm, Jared S.
Abstract:: The behavior of the thin liquid ﬁlm formed between a bubble and hydrophobic membrane is of high interest in applications where separating two-phase mixtures is beneﬁcial. One such application is in-situ vapor extraction heat sinks. In these systems, high heat transfer rates are accomplished by taking advantage of the high...
Resource Type:: Masters Thesis
Full Text:: AN ABSTRACT OF THE THESIS OF Jared S. Bahm for the degree of

Biological insertion of nanostructured germanium and titanium oxides into diatom biosilica

Creator:: Jeffryes, Clayton S.
Abstract:: There is significant interest in titanium oxide and germanium-silicon oxide nanocomposites for optoelectronic, photocatalytic, and solar cell applications. The ability of the marine diatom Pinnularia sp. to uptake soluble metal oxides from cell culture medium, and incorporate them into the micro- and nano-structure of their amorphous silica cell walls, called...
Resource Type:: Dissertation
Full Text:: Clayton S. Jeffryes for the degree of Doctor of Philosophy in Chemical Engineering presented on May 26

Fabrication of Cost-effective Flexible Glucose Sensor for Continuous Glucose Monitoring

Creator:: Mullapudi, Sri Sai Kameswara
Abstract:: Diabetes is a pandemic that affects nearly 29.1 million Americans and the fourth leading cause of mortality in the US. Type 1 diabetes is a chronic condition which occurs due to little to no production of insulin by the pancreas. This form of diabetes requires constant monitoring of blood glucose...
Resource Type:: Masters Thesis
Full Text:: for each of the professors that I took classes from and Drs. Greg Herman, Larry Cheng, Adam Higgins

Mitochondrial decay in the aging rat heart : changes in fatty acid-supported bioenergetics and macromolecular organization of the electron transport system

Creator:: Gómez Ramirez, Luis A.
Abstract:: Decline in cardiac pump function is a hallmark of aging where mitochondrial decay is an important underlying cause. Although certainly multifactorial in nature, both dysfunction of the machinery involved in the chemiosmotic process of energy transduction and lower capacity to maintain fatty acid-driven respiration are identified as intrinsic factors of...
Resource Type:: Dissertation
Full Text:: research committee, Drs. Claudia S. Maier, Balz Frei, Joseph Beckman and Adam Higgins not only for

Experimental study of subcooled water spray cooling using flow symmetric micro-structured surfaces

Creator:: Tulchinsky, Alex M.
Abstract:: Spray impingement cooling has been shown to be a leading candidate for future high heat flux cooling applications. In general, spray cooling curves consist of three heat flux regimes; single-phase, two-phase and critical heat flux (CHF). CHF is considered the design limit for almost all two-phase cooling applications, as a...
Resource Type:: Masters Thesis
Full Text:: m 3 /m 2 s. Convection coefficients, cvh , and spray efficiencies, η, are also presented for

Chandler Loop Model for the Development of Dynamic Hemocompatibility Assays

Creator:: Hasbrook, AnneMarie V.
Abstract:: A common issue with extracorporeal medical devices is blood clotting due to bio-incompatibility. Systemic anticoagulants are often prescribed to mitigate the coagulation issues. However, such drugs can lead to further complications, for example hemorrhaging. One solution to improve the hemocompatibility of blood-contacting medical devices are biomaterials, such as slippery liquid...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Adam Z. Higgins, Committee Member, representing Bioengineering

ScholarsArchive@OSU

Machine learning approach to improve drug discovery in natural product extracts

Ink and Substrate Compatibility for Electrochemical Sensing in Paper-based Devices

Oxidation of Amorphous Metal Alloy Surfaces Studied Using Ambient Pressure X-Ray Photoelectron Spectroscopy

Optimal control of an underactuated bipedal robot

Modelling Thin Liquid Film Draining of Bubbles on Porous Media in Confined Geometry

Biological insertion of nanostructured germanium and titanium oxides into diatom biosilica

Fabrication of Cost-effective Flexible Glucose Sensor for Continuous Glucose Monitoring

Mitochondrial decay in the aging rat heart : changes in fatty acid-supported bioenergetics and macromolecular organization of the electron transport system

Experimental study of subcooled water spray cooling using flow symmetric micro-structured surfaces

Chandler Loop Model for the Development of Dynamic Hemocompatibility Assays

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