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Filtering by: Creator Kent, Adam J. R. Remove constraint Creator: Kent, Adam J. R. Committee Member Higgins, Adam Z. Remove constraint Committee Member: Higgins, Adam Z.

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  • Technology to promote concept-based, active learning and enable education research

    Creator:
    Brooks, Bill J.
    Abstract:
    This dissertation centers on development of two web-based, in class learning tools, the AIChE Concept Warehouse (CW) and the Web-based Interactive Science and Engineering Learning Tool (WISE), and describes the investigation of student learning through their use. The intent of these tools is to promote deeper conceptual understanding in students...
    Resource Type:
    Dissertation
    Full Text:
    and Enable Education Research AN ABSTRACT OF THE DISSERTATION OF Bill J

  • Synthesis and anticoagulant function of heparin containing block copolymers on polystyrene microspheres

    Creator:
    Fry, Allyson Kaye
    Abstract:
    Contact of blood with the surfaces of synthetic materials is associated with spontaneous protein adsorption, initiating platelet aggregation, the coagulation cascade, and the eventual development of a stable clot. Current therapy to inhibit implant-induced thrombosis is life-long administration of systemic anticoagulants. An alternative to the systemic administration of anticoagulant drugs...
    Resource Type:
    Masters Thesis

  • Surface Characterization of Engineered Biomaterials

    Creator:
    Faase, Ryan A.
    Abstract:
    The work presented in this dissertation highlights the various techniques available to characterize the increasingly complex surfaces of engineered biomaterials. The methods used range from the simple measurement of a contact angle with a smartphone to a complex synchrotron technique like near edge x-ray absorption fine structure (NEXAFS) spectroscopy to...
    Resource Type:
    Dissertation
    Full Text:
    (2019). 6 Brash, J. L., Horbett, T. A., Latour, R. A. & Tengvall, P. The blood compatibility

  • Single Phase and Flow Boiling Heat Transfer and Flow Characterization in Microscale Pin Fin Heat Sinks

    Creator:
    Rasouli, Erfan
    Abstract:
    The ever increasing requirements for heat dissipation in various thermal management applications such as computer chip cooling and high power electronics have necessitated the need for novel thermal management techniques. Thermal management using heat sinks with microscale features is amongst the prominent techniques developed over the past two decades. In...
    Resource Type:
    Dissertation
    Full Text:
    Pence, Dr. Kendra Sharp, Dr. Sourabh Apte, and my GCR Dr. Adam Higgins for taking the time to review

  • Role of P2Y₁₂ Inhibition in PAR1 Stimulated Platelet Dense Granule Release

    Creator:
    Laschober, Nicole B.
    Abstract:
    Platelet activation uses a complex set of pathways to respond to vascular injury during hemostasis. However, thrombosis relies on the same set of pathways. Antiplatelet therapies used to prevent thrombotic events often target the P2Y₁₂ platelet receptor for inhibition but can result in bleeding diathesis or in abnormally high ADP...
    Resource Type:
    Honors College Thesis
    Full Text:
    signaling with MRS2395," Platelets, vol. 29, no. 4, pp. 383-394, 2018. [2] S. A. Smith, R. J. Travers

  • Role of Alloying on the Thermal Stability of Duplex Stainless Steel

    Creator:
    Garfinkel, David
    Abstract:
    Duplex stainless steels (DSS) are an attractive potential material in nuclear power generation systems due to an excellent combination of corrosion resistance, strength, toughness, and affordability. Thermal embrittlement caused by phase instability in the temperature range of ~300-550°C severely limits the service temperature of DSS. The rate of embrittlement varies...
    Resource Type:
    Masters Thesis
    Full Text:
    Fei Teng and Ben Adam for providing me with assistance whenever it was needed. Finally, I would

  • Probing the Biophysical interactions of Anti-Microbial Peptide WLBU2 Using Model Membrane Systems

    Creator:
    Golbek, Thaddeus W.
    Abstract:
    WLBU2 is an engineered cationic amphiphilic peptide that targets Gram-positive and Gram-negative bacteria, and envelopes endotoxin while avoiding other cell types. The exact mechanism of how WLBU2 targets, binds, and disrupts bacterial cell membranes is still not completely known. Thus, the overall goal of this investigation is to determine the...
    Resource Type:
    Masters Thesis
    Full Text:
    . Nature. 2002, 415, 389-395. 3. Marr, A. K.; Gooderham, W. J.; Hancock, R. E. W. Antibacterial

  • Precision Medicine for the Intervertebral Disc: Image Processing and Computational Modeling of Disc Degeneration to Inform Patient-Specific Therapies

    Creator:
    Ahrens, Sonia R.
    Abstract:
    The human intervertebral disc is a deceptively simple structure which plays an essential role in human movement. Even slight changes to the disc microenvironment can have far reaching consequences, particularly when these changes result in disc degeneration and herniation. Degeneration is increasingly tied to lower back pain; better understanding this...
    Resource Type:
    Masters Thesis
    Full Text:
    metabolism of the intervertebral disc: J.G. Urban,59,60 Stephen J. Ferguson,61 Andrea Malandrino,62 and

  • Oxidation of Amorphous Metal Alloy Surfaces Studied Using Ambient Pressure X-Ray Photoelectron Spectroscopy

    Creator:
    Alzaga Elizondo, Pedro
    Abstract:
    Amorphous metal thin films (AMTFs) are of growing interest due to their unique mechanical properties and chemical stability. AMTFs have an advantage over polycrystalline metal films due to the lack of grain boundaries which gives AMTFs added durability and relatively smoother surfaces. For this reason, AMTFs have been investigated as...
    Resource Type:
    Masters Thesis
    Full Text:
    Herman’s Research group. I would especially like to thank Dr. J. Trey Diulus for the training and

  • Optimal control of an underactuated bipedal robot

    Creator:
    Jones, Mikhail S.
    Abstract:
    Bipedal robots represent a unique class of control problems that combine many of the most difficult elements of nonlinear control. These robots are typically designed to be mobile and as such have limited energy and actuator authority making efficiency a prime concern. Unlike wheeled robots, legged robots must transition between...
    Resource Type:
    Masters Thesis
    Full Text:
    time t0, and terminal time tf that minimizes the scalar performance index J = Φ(x(t0), t0,x(tf ), tf