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Filtering by: Creator Maier, Claudia Remove constraint Creator: Maier, Claudia Committee Member Ho, Emily Remove constraint Committee Member: Ho, Emily File Format application/pdf Remove constraint File Format: application/pdf

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  • Activation, incorporation and modification of capreomycidine during viomycin biosynthesis

    Creator:
    Fei, Xiaobo
    Abstract:
    Molecular genetic and enzymological techniques have been employed to study antibiotic biosynthesis. The nonproteinogenic amino acid capreomycidine is the signature residue found in the tuberactinomycin family of antitubercular peptide antibiotics and an important element of the pharmacophore. Recombinant VioG, a single module peptide synthetase from the viomycin gene cluster cloned...
    Resource Type:
    Masters Thesis
    Full Text:
    . Maier, and Dr. Rockey for their guidance and assistance throughout my graduate studies. I would like