Index Catalog // ScholarsArchive@OSU

Modulation of metabolic syndrome by soy isoflavones : in-vitro and in-vivo models

Creator:: Luo, Ting
Abstract:: Metabolic syndrome is a problem affecting people around the world. In a number of studies, soy intake has been documented to possess antidiabetic and anticardiovascular effect. My project is focused on the impact of the intake of compounds found within soy, the isoflavones, their impact on metabolic syndrome symptoms, and...
Resource Type:: Dissertation

Metabolic and Renal Effects of Consumption of Five Phytochemicals in High-Fat Fed C57BL6J Mice

Creator:: Hansen, Allysa
Abstract:: A significant body of research demonstrates that phytochemical intake favorably influences hepatic metabolism via a number of different biological mechanisms. Other research has shown a positive effect of certain phytochemicals on kidney health, specifically in ameliorating symptoms of kidney disease. The current research used three separate studies that tested the...
Resource Type:: Masters Thesis
Full Text:: (Moore, 2010). Fat accumulates in the liver due to the dysregulation of fatty acid influx to the

Dietary organosulfur and organoselenium compounds as HDAC inhibitors

Creator:: Nian, Hui
Abstract:: Histone deacetylase (HDAC) inhibitors have the potential to de-repress epigenetically silenced genes in cancer cells, leading to cell cycle arrest and apoptosis. Dietary HDAC inhibitors derived from natural phytochemicals are promising anticancer agents. In this thesis, metabolites from natural organosulfur and organoselenium compounds, i.e. allyl mercaptan (AM), β-methylselenopyruvate (MSP) and...
Resource Type:: Dissertation

Oxidative stress and muscle dysfunction following anterior cruciate ligament surgery

Creator:: Barker, Tyler
Abstract:: Despite the advances in surgery, physical therapy, and pharmaceutical agents, muscle dysfunction (i.e., atrophy and weakness) continues to impair recovery from an anterior cruciate ligament (ACL) injury and surgery. Ischemia-reperfusion injury during surgery and the subsequent limb disuse are two events experienced by patients having ACL surgery. Oxidative stress and...
Resource Type:: Dissertation

Understanding health behavior influences of undergraduate students during college transition

Creator:: Hart, Kerry A.
Abstract:: As college students transition to life away from their parental home, the need to make independent decisions regarding their eating and exercise behaviors is evident. This life transition may be a critical period for establishment of long term behavior patterns with potential impact on health, disease and weight balance. This...
Resource Type:: Masters Thesis
Full Text:: , 2004; Hoffman, Policastro, Quick, & Lee, 2006; Mihalopoulos, Auinger, & Klein, 2008; Brown, 2008

In Utero Exposure to Arsenic and Mercury : Epigenome-Wide Associations and Newborn Health Outcomes

Creator:: Cardenas, Andres
Abstract:: Mercury and arsenic are known developmental toxicants and environmental exposures are ubiquitous worldwide from natural and anthropogenic sources. Prenatal exposure to both contaminants are independently associated with adverse perinatal health outcomes and latent disease risk that could be in part mediated by epigenetic reprogramming events. Fetal programming events involving DNA...
Resource Type:: Dissertation
Full Text:: fractions of MMA in the urine compared to men (Hopenhayn-Rich, Biggs, Smith, Kalman, & Moore, 1996

Roles for retinoid-X-receptors in solar UV-induced melanocyte homeostasis and melanomagenesis

Creator:: Coleman, Daniel J.
Abstract:: Melanoma is the deadliest form of skin cancer, arising from malignant transformation of pigment-producing melanocytes. The primary risk factor for melanoma and other skin cancers is DNA damage resulting from unprotected solar ultraviolet radiation (UVR). If incorrectly repaired, this damage can result in incorporation of mutations that cause aberrant cell...
Resource Type:: Dissertation

Polyunsaturated fatty acid synthesis and type 2 diabetes complications

Creator:: Tripathy, Sasmita
Abstract:: Type 2 diabetes mellitus (T2DM) is a disease of multi-complications affecting more than 20 million US adults. Hyperglycemia is the classic clinical feature of diabetes, and uncontrolled hyperglycemia leads to deadly health complications. Thus, control of blood glucose represents a major goal for diabetics. Human and rodent studies revealed another...
Resource Type:: Dissertation

Efficacy of the Wellness Focused “Be Orange Challenge” with Tracking to Promote Healthy Behavior Change

Creator:: Miller, Aimee S.
Abstract:: Purpose: Many programs are available to engage people in health-promoting behaviors or behavior change, but most target specific behavior outcomes (e.g., weight loss, smoking cessation) rather than wellness. This study aimed to assess the effectiveness of a tracking-based health challenge focused on overall wellness, with or without peer support. Methods:...
Resource Type:: Honors College Thesis
Full Text:: collaboration with the Faculty Staff Fitness program and the Moore Family Center. All adults (age 18 or older

Metabolic Effects in C57B/6J Mice Fed a High-Fat Diet Supplemented With Walnuts, Raspberries and Other Whole Foods

Creator:: Miranda-Garcia, Omar
Abstract:: Health benefits obtained from consumption of fruits and vegetables have the potential to improve the lifestyle of individuals. The walnut is a polyunsaturated fatty acid (PUFA)-rich whole food that is readily available in the U.S and has been shown to potentially reduce risk of Metabolic Syndrome. Furthermore, consumption of polyphenol...
Resource Type:: Masters Thesis

ScholarsArchive@OSU

Modulation of metabolic syndrome by soy isoflavones : in-vitro and in-vivo models

Metabolic and Renal Effects of Consumption of Five Phytochemicals in High-Fat Fed C57BL6J Mice

Dietary organosulfur and organoselenium compounds as HDAC inhibitors

Oxidative stress and muscle dysfunction following anterior cruciate ligament surgery

Understanding health behavior influences of undergraduate students during college transition

In Utero Exposure to Arsenic and Mercury : Epigenome-Wide Associations and Newborn Health Outcomes

Roles for retinoid-X-receptors in solar UV-induced melanocyte homeostasis and melanomagenesis

Polyunsaturated fatty acid synthesis and type 2 diabetes complications

Efficacy of the Wellness Focused “Be Orange Challenge” with Tracking to Promote Healthy Behavior Change

Metabolic Effects in C57B/6J Mice Fed a High-Fat Diet Supplemented With Walnuts, Raspberries and Other Whole Foods

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