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Filtering by: Subject Phenylbutazone -- Physiological effect Remove constraint Subject: Phenylbutazone -- Physiological effect Committee Member Ho, Emily Remove constraint Committee Member: Ho, Emily Resource Type Masters Thesis Remove constraint Resource Type: Masters Thesis

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  • Metabolic effects of consumption of quercetin, ellagic acid, cherry, and apple phytochemical extracts in high-fat fed mice

    Creator:
    Smith, Sarah M.
    Abstract:
    Metabolic improvements and changes in gene expression were measured in mice fed polyphenol-rich extracts derived from apples and sweet cherries, and the common phytochemicals, quercetin and ellagic acid. Polyphenol-rich extracts were produced by solid phase extraction and column chromatography. Extracts and purified compounds were mixed into a high-fat (HF, 60%...
    Resource Type:
    Masters Thesis
    Full Text:
    line model will be used to measure physiological and molecular parameters. 1.1 Metabolic Disease

  • Sesame oil increases plasma γ-tocopherol and inhibits γ-tocopherol metabolism in humans

    Creator:
    Lee, Sangeun
    Abstract:
    In rats, sesame lignans increase plasma γ-tocopherol concentrations and inhibit γ-tocopherol degradation to its metabolite γ-carboxyethylhydroxychroman (γ-CEHC). To test if sesame lignan consumption inhibits γ- tocopherol metabolism in humans, muffins prepared with either corn oil (control) or sesame oil and an equimolar mixture of deuterium labeled d6-α- and d2-γ- tocopheryl...
    Resource Type:
    Masters Thesis
    Full Text:
    ................................................................................. 7 γ-Tocopherol’s physiologic effect on human health

  • The role of lutein and zeaxanthin in protecting the retina from light damage

    Creator:
    Derenick, Rhianna A.
    Abstract:
    Purpose: The xanthophyll carotenoids lutein and zeaxanthin are concentrated in the macula lutea of the retina. It is thought that the two plant pigments may play a role in preventing the development of age-related macular degeneration (AMD). Exposure to damaging light plays a role in retinal deterioration and AMD. The...
    Resource Type:
    Masters Thesis
    Full Text:
    can examine biochemical, physiological and dietary mechanisms of carotenoids and light damage at

  • Metabolic and Renal Effects of Consumption of Five Phytochemicals in High-Fat Fed C57BL6J Mice

    Creator:
    Hansen, Allysa
    Abstract:
    A significant body of research demonstrates that phytochemical intake favorably influences hepatic metabolism via a number of different biological mechanisms. Other research has shown a positive effect of certain phytochemicals on kidney health, specifically in ameliorating symptoms of kidney disease. The current research used three separate studies that tested the...
    Resource Type:
    Masters Thesis
    Full Text:
    positive effect of certain phytochemicals on kidney health, specifically in ameliorating symptoms of

  • Contractile function and calpain activity in mouse skeletal muscle during hypoxia

    Creator:
    Hu, Hui
    Abstract:
    Calcium activated proteases, or calpains, are activated in cardiac muscles under conditions of ischemia/reperfusion and hypoxia. Their activity in skeletal muscle under similar conditions is poorly understood. We tested the hypothesis that hypoxia elevates calpain-mediated proteolysis in isolated glycolytic (extensor digitorum longus, EDL) and oxidative (soleus, SOL) mouse muscles studied...
    Resource Type:
    Masters Thesis
    Full Text:
    increase. However, inhibition of calpain activity had no effect on peak power output and isometric force