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Filtering by: Subject Fatty acids -- Metabolism Remove constraint Subject: Fatty acids -- Metabolism Committee Member Ho, Emily Remove constraint Committee Member: Ho, Emily

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  • DHA and Low-fat Low-cholesterol Diets as Treatment Strategies for Nonalcoholic Fatty Liver Disease

    Creator:
    Lytle, Kelli Anne
    Abstract:
    Nonalcoholic fatty liver disease (NAFLD) is characterized by the accumulation of excess neutral lipids within the parenchymal cells of the liver. The primary etiology is diet-induced and most often exists as a comorbidity with obesity, metabolic syndrome, and/or Type 2 Diabetes. The development of excess liver lipid can be self-limiting...
    Resource Type:
    Dissertation
    Full Text:
    acid (DHA), a long chain omega-3 polyunsaturated fatty acid (ω3 PUFA). This molecule has broad

  • Long-chain (n-3) PUFA and non-alcoholic fatty liver disease

    Creator:
    Depner, Christopher Michael
    Abstract:
    Non-alcoholic fatty liver disease (NAFLD) is defined as excess hepatic lipid accumulation, in the absence of excess alcohol consumption and chronic liver disease. NAFLD can range in severity from simple fatty liver (steatosis) to non-alcoholic steatohepatitis (NASH). NASH is defined as hepatic steatosis with inflammation and hepatic injury and describes...
    Resource Type:
    Dissertation
    Full Text:
    disrupted balance of fatty acid metabolism in the liver. Liver fatty acid sources include circulating non

  • Polyunsaturated fatty acid synthesis and type 2 diabetes complications

    Creator:
    Tripathy, Sasmita
    Abstract:
    Type 2 diabetes mellitus (T2DM) is a disease of multi-complications affecting more than 20 million US adults. Hyperglycemia is the classic clinical feature of diabetes, and uncontrolled hyperglycemia leads to deadly health complications. Thus, control of blood glucose represents a major goal for diabetics. Human and rodent studies revealed another...
    Resource Type:
    Dissertation
    Full Text:
    ........................................................................................ 23 Fig 1.3: Transcription factors regulation of hepatic fatty acid metabolism ..... 24 Fig 1.4