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Filtering by: Creator Burley, Stephen K. Committee Member Hsu, Victor

Two new roles for the TYMV tRNA-like structure : translation enhancement and repression of minus strand synthesis

Creator:

Matsuda, Daiki

Abstract:

Some positive-strand RNA plant viruses possess a transfer RNA-like structure (TLS) at the 3'-terminus of their genomic RNAs. The closest mimicry to tRNA is exhibited by the valylatable TLSs from tymoviruses and furo-like viruses, which are able to interact with key cellular tRNA enzymes: [CTP, ATP]:tRNA nucleotidyltransferase (CCA NTase), valyl-tRNA...

Resource Type:

Dissertation

Full Text:

Chapter 2. L. Bauer and K. Tinnesand assisted with construction of transcription vectors used in Chapter
Exploring Protein Structure: Seeing the Forest and the Trees

Creator:

Brereton, Andrew E.

Abstract:

Life on Earth intimately depends on the function of countless proteins. For the majority of studied proteins, function absolutely depends on conformation (i.e. 3-dimensional shape in solution). The exact nature of how a protein goes from an unfolded linear polypeptide chain to an organized folded molecule is still not known,...

Resource Type:

Dissertation
Binding and assembly of H5 (and the globular domain of H5) onto DNA

Creator:

Carter, George John

Abstract:

In order to better characterize linker histone interactions with DNA, avian erythrocyte-specific linker H5 and the trypsin-resistant globular domain of H5 (GH5) were used in DNA binding studies. To begin, H5 displayed a considerably higher binding affinity for DNA than the isolated globular domain (GH5), supporting the importance of the...

Resource Type:

Dissertation