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Filtering by: Creator Bisson, Casey Committee Member Hsu, Victor L. Degree Name Doctor of Philosophy (Ph.D.)

Characterization of the Mechanisms of Action and Molecular Targets of Hop-derived Flavonoids in the Mitigation of Obesity-related Metabolic Impairments

Creator:

Paraiso, Ines L.

Abstract:

Obesity is a complex multifactorial disease resulting from excessive energy intake compared to energy expenditure. The excess energy is mostly stored as fat in enlarged adipocytes, but some lipids may infiltrate other organs such as the liver to form ectopic fat. Adipose tissue and ectopic fat produce and secrete a...

Resource Type:

Dissertation

Full Text:

, V. L. Hsu, W. H. Bisson, and C. S. Maier. 2016. Conformational modulation of the farnesoid X
Label-free mass spectrometry-driven methods for elucidating adaptive responses of the hepatic mitochondrial proteome in an alcoholic fatty liver disease model

Creator:

Tzeng, Shin-Cheng

Abstract:

Alcoholic liver disease (ALD) continues to be one of the major public health problems in the United States and worldwide. Complicated by factors including gender, polymorphisms of alcohol-metabolizing enzymes, immunologic factors, exposures to other substances/drugs, hepatic viral infections, nutritional deficiencies, and obesity, ALD is a complex disease that requires a...

Resource Type:

Dissertation

Full Text:

. and C.A. Casey, Dangerous byproducts of alcohol breakdown--focus on adducts. Alcohol Res Health