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Filtering by: Creator Moore, Paul Harris Committee Member Ishmael, Jane E. Degree Field Pharmaceutical Sciences

Characterization of the Mechanisms of Action and Molecular Targets of Hop-derived Flavonoids in the Mitigation of Obesity-related Metabolic Impairments

Creator:

Paraiso, Ines L.

Abstract:

Obesity is a complex multifactorial disease resulting from excessive energy intake compared to energy expenditure. The excess energy is mostly stored as fat in enlarged adipocytes, but some lipids may infiltrate other organs such as the liver to form ectopic fat. Adipose tissue and ectopic fat produce and secrete a...

Resource Type:

Dissertation

Full Text:

to the analysis of Chapter 3. Luce Mattio and Paul Blakemore performed the chemical synthesis of
Drug Discovery and Chemical Ecology Investigations of Specialized Metabolism in Tolypocladium and Paraisaria

Creator:

Tehan, Richard M.

Abstract:

Since the discovery of penicillin in 1928, the fungal kingdom has remained a fertile source for the discovery of new, biologically active, natural products. Further, as natural products continue to be discovered from fungi, a deeper understanding of the critical role of specialized metabolism in fungal ecology is afforded. The...

Resource Type:

Dissertation