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Filtering by: Creator McGrath, Daniel Committee Member Johnson, Colin Decade 2010-2019

New Treatments for HIV and Cancer: Uncovering Bioactive Compounds from Small Molecule Sources

Creator:

Overacker, Ross D.

Abstract:

Small molecule drugs have been instrumental in our fight against diseases, beginning when some of the earliest ancient cultures used plant remedies to treat illnesses. More recently, the skill of isolating and characterizing the active ingredients within bioactive plants and microbial extracts has led to the isolation and design of...

Resource Type:

Dissertation

Full Text:

ABSTRACT OF THE DISSERTATION OF Ross Daniel Overacker for the degree of Doctor of Philosophy in Chemistry
Analysis of Cancer Progression by Establishing Quantitative Assessments of Zebrafish Xenografts

Creator:

Gamble, John T.

Abstract:

The goal of this dissertation was to improve our abilities in acquiring critical in vivo data by establishing embryo-larva zebrafish as an exemplary model to quantitatively evaluate cancer progression. The living environment that encompasses a tumor has a significant effect on how cancer develops, grows and metastasizes. In order to...

Resource Type:

Dissertation

Full Text:

members Hyo Sang Jang, Martin Pearce, Jessica Phillips, Bach Nguyen, Veronica Puig Sanvicens, Daniel