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Filtering by: Creator Martin, Olga Committee Member Kioussi, Chrissa Decade 2000-2009

Characterization of the mechanism and function of C₂H₂ zinc finger protein CTIP2 in the developmental processes

Creator:

Golonzhka, Olga

Abstract:

CTIP2 is a C2H2 zinc finger transcription factor that plays important yet poorly understood roles in mouse development. CTIP2 is known to be highly expressed in the central nervous system, skin and T lymphocytes during embryogenesis. CTIP2-null mice die perinatally of unknown causes and exhibit defects in multiple organ systems...

Resource Type:

Dissertation

Full Text:

. ©Copyright by Olga Golonzhka June 9, 2008 All Rights Reserved
In vitro and in vivo approaches for the functional characterization of the scaffold protein, GRASP

Creator:

Venkataraman, Anand

Abstract:

Studies using the pluripotent embryonic carcinoma cell line, P19, as a retinoic acid (RA)-responsive model system have been instrumental towards our understanding of the RA-dependent signaling pathways in development and homeostasis. Grp1-associated scaffold protein (GRASP; also known as Tamalin) was first identified by our group, as a gene robustly induced...

Resource Type:

Dissertation

Full Text:

lab members (Dr. Acharawan Topark-Ngarm, Dr. Olga Golonzhka, Dr. Lingjuan Zhang, Mr. Xiao Liu, Mr