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Characterization of the mechanism and function of C₂H₂ zinc finger protein CTIP2 in the developmental processes

Creator:

Golonzhka, Olga

Abstract:

CTIP2 is a C2H2 zinc finger transcription factor that plays important yet poorly understood roles in mouse development. CTIP2 is known to be highly expressed in the central nervous system, skin and T lymphocytes during embryogenesis. CTIP2-null mice die perinatally of unknown causes and exhibit defects in multiple organ systems...

Resource Type:

Dissertation

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. ©Copyright by Olga Golonzhka June 9, 2008 All Rights Reserved
In vitro and in vivo approaches for the functional characterization of the scaffold protein, GRASP

Creator:

Venkataraman, Anand

Abstract:

Studies using the pluripotent embryonic carcinoma cell line, P19, as a retinoic acid (RA)-responsive model system have been instrumental towards our understanding of the RA-dependent signaling pathways in development and homeostasis. Grp1-associated scaffold protein (GRASP; also known as Tamalin) was first identified by our group, as a gene robustly induced...

Resource Type:

Dissertation

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lab members (Dr. Acharawan Topark-Ngarm, Dr. Olga Golonzhka, Dr. Lingjuan Zhang, Mr. Xiao Liu, Mr
The role of the transcriptional regulatory protein BCL11B in dental and craniofacial development

Creator:

Kyrylkova, Kateryna

Abstract:

BCL11B is a transcriptional regulatory protein that plays essential roles during mouse embryonic development. BCL11B is expressed and functions in the immune and nervous systems as well as within ectodermal organs. Multiple studies have characterized the roles of BCL11B in T cells, brain, and skin. However, very little is known...

Resource Type:

Dissertation

Full Text:

and creating a great environment at the department Former lab members, including Dr. Olga