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Filtering by: Creator Fernandez Sanchez, Jose Luis Committee Member Kolluri, Siva

Harnessing Heterogeneity in Human Gut Microbiome Data

Creator:

Tataru, Christine

Abstract:

The focus of this thesis is to design, characterize, and apply novel computational methods and molecular systems to interrogate heterogeneous human gut microbiome-related phenomena. In Chapter 2, I design, implement, and characterize a method for embedding co-occurrence patterns derived from massive 16s amplicon datasets. I use this method to 1....

Resource Type:

Dissertation
Nanoparticle features and their relative influence on biological responses

Creator:

Denluck, Lindsay

Abstract:

Nanoparticles (NPs), defined as materials having at least one dimension (height, width, diameter) in the nanoscale, are increasingly being incorporated into a wide variety of products and are replacing traditional bulk materials in many applications. This is because they can be more efficacious, more sustainable, and can have unique characteristics...

Resource Type:

Dissertation
Towards a Better Understanding of How the Dietary Supplement Xanthohumol Can Improve Health

Creator:

Logan, Isabelle E.

Abstract:

Xanthohumol, a prenylated flavonoid found in hops and beer, possesses a long-standing reputation to improve health. Xanthohumol’s cytotoxicity to a wide variety of cancer cell lines is well-established. Herein we provide further insight into the cytotoxicity of not only xanthohumol, but also its non-estrogenic derivatives, to a number of colonic...

Resource Type:

Dissertation