Search Constraints

Start Over
Filtering by: Creator Pennington-Lehman, Heather Remove constraint Creator: Pennington-Lehman, Heather Committee Member Kolluri, Siva Remove constraint Committee Member: Kolluri, Siva

Search Results

  • Employing Genetic Code Expansion Tools to Elucidate Disease Mechanisms and Generate New Therapeutics

    Creator:
    Van Fossen, Elise M.
    Abstract:
    In biology, function and disease are closely intertwined, requiring the coordination of hundreds of intricate chemical reactions. Interdisciplinary cooperation between chemical and biological approaches is necessary to decipher the chemical links between physiological and pathological conditions. In this arena, the precision tools made possible with chemical biology can manipulate and...
    Resource Type:
    Dissertation
    Full Text:
    treasure your friendship forever. An especial thank you to Heather, Margaux, Shauna, Kasie and Savanna

  • Harnessing Heterogeneity in Human Gut Microbiome Data

    Creator:
    Tataru, Christine
    Abstract:
    The focus of this thesis is to design, characterize, and apply novel computational methods and molecular systems to interrogate heterogeneous human gut microbiome-related phenomena. In Chapter 2, I design, implement, and characterize a method for embedding co-occurrence patterns derived from massive 16s amplicon datasets. I use this method to 1....
    Resource Type:
    Dissertation