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Filtering by: Subject Zebra danio -- Genetics Committee Member Kolluri, Siva

Chemical and biological approaches to identify vertebrate tissue regeneration pathways

Creator:

Sengupta, Sumitra

Abstract:

Numerous human conditions would be improved if therapies to encourage tissue regeneration were available. The goal of regenerative medicine is to encourage the body's intrinsic ability to repair and restore tissues lost by disease, injury or aging. While certain vertebrates have the inherent capacity to regenerate, mammals do not. To...

Resource Type:

Dissertation

Full Text:

and spinal cord. The organization of the genome and the genetic pathways involved with signal
Classifying Chemical Bioactivity by Coupling High-throughput Phenotypic Anchoring and Transcriptome Profiling in Zebrafish

Creator:

Haggard, Derik

Abstract:

There are more than 87,000 chemicals in current use with little to no toxicity information available. Assessing such a large number of chemicals using traditional methods would take an unreasonable amount of time and money, and require the use a large number of animals. The incorporation of high-throughput in vivo...

Resource Type:

Dissertation

Full Text:

et al., 2003; Cox and Goessling, 2015). Humans and zebrafish share ~70% of genetic homology and ~82
Developing rapid in vivo assays to investigate structure response relationships

Creator:

Truong, Lisa

Abstract:

Incorporation of nanoparticles (NPs) into consumer products is on the rise and human exposure to NPs is unavoidable. Currently, there is insufficient data to assess the safety of nanoparticles. I conducted a series of five studies using the zebrafish model to determine which NP components (i.e., core material or surface...

Resource Type:

Dissertation

Full Text:

Vivo Toxicity of Silver Nanoparticles and Silver Ions in Zebrafish (Danio rerio). Journal of