Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Creator Fernández Sánchez, José Luis Committee Member Leid, Mark Non-Academic Affiliation Oregon State University. Graduate School

Investigations of regulatory T cell induction by 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin during a graft-versus-host response

Creator:

Marshall, Nikki B.

Abstract:

The immune toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) has been studied for over 35 years, but only recently has the profound immune suppression associated with TCDD exposure been linked to induction of regulatory T cells (Tregs). The effects of TCDD are mediated through binding the aryl hydrocarbon receptor (AhR), a ligand-activated transcription...

Resource Type:

Dissertation

Full Text:

expression in hematopoietic cells (Fernandez-Salguero et al., 1996; Staples et al., 1998). AhR is
Characterization of the Mechanistic Basis for the Cytotoxic Activity of Select Macrocyclic Natural Products against Glioblastoma Cells

Creator:

Serrill, Jeffrey D.

Abstract:

Natural products from both terrestrial and marine sources represent a significant source of novel drug leads, and have previously been developed into clinically-approved agents for the treatment of various human diseases. This work represents the biological characterization of the mechanistic basis for activity of several natural product structures in models...

Resource Type:

Dissertation

Full Text:

. Science 260(5105): 214 216. 9. Urdiales JL, Morata P, Núnez De Castro I, Sánchez –Jimínez F. (1996