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Filtering by: Creator Brown, Pia Tollo Committee Member Leid, Mark

Regulation of neuronal A₁ adenosine receptors

Creator:

Hettinger, Barbara D.

Resource Type:

Dissertation

Full Text:

-phenylisopropyl-adenosine (R PIA)> 5'-N-ethylcarboxamide adenosine (NECA)>S-phenylisopropyladenosine (S-PIA
Some potential mechanisms for finely-tuned regulation of phospholipase C-β isozymes : studies of dimerization and phosphatidylinositol 3,4,5-trisphosphate activation

Creator:

Zhang, Yong

Abstract:

Phospholipase C-β (PLC-β) isozymes are key effectors in G protein-coupled signaling pathways. Prior research suggested that some isoforms of PLC-β may exist and function as dimers, but little is known about dimerization of PLC-β. Data from coimmunoprecipitation assays of differentially-tagged PLC-β constructs and sizeexclusion chromatography of native PLC-β support homodimerization...

Resource Type:

Dissertation

Full Text:

, which is consistent with another report in which Gαi2 and PLC-β3 antibody inhibited R-PIA (the