Index Catalog // ScholarsArchive@OSU

Creator:: Grochowski, Laura L.
Abstract:: Molecular genetic and enzymological techniques have been employed to study secondary metabolite biosynthesis. These investigations have focused on two projects: the cloning and heterologous expression of biosynthetic gene clusters from unculturable marine organisms and the characterization of individual enzymes involved in the biosynthesis of the antifungal agent blasticidin S. The...
Resource Type:: Dissertation
Full Text:: groups, especially Dr. Mike Jackson, Dr. Youhhi Woo, Dr. Chanokpom (Shiny) Phaosiri, Dr. Dojung Kim

Creator:: Myzak, Melinda C.
Abstract:: Targeting the epigenome, including the use of histone deacetylase (HDAC) inhibitors, is a novel strategy for cancer chemoprevention. Sulforaphane (SFN), a compound found at high levels in broccoli and broccoli sprouts, is a potent inducer of Phase 2 detoxification enzymes and inhibits tumorigenesis in animal models. SFN also has a...
Resource Type:: Dissertation

Creator:: Gilmore, Barbara S.
Abstract:: White mold, caused by Sclerotinia sclerotiorum (Lib.) De Bary, is a destructive yield-limiting disease of common bean (Phaseolus vulgaris L.). Genetic resistance to this pathogen is limited in common bean. Identification of high levels of partial physiological resistance in a genetically cross compatible species, Phaseolus coccineus, is advisable. The objectives...
Resource Type:: Dissertation

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