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Filtering by: Advisor Frederick, W. James Committee Member Lesser, Virginia

A novel self-sealing chewable sustained release tablet of acetaminophen ; Development and evaluation of novel itraconazole oral formulations ; A novel zero order release matrix tablet

Creator:

Rakkanka, Vipaporn

Abstract:

This thesis describes evaluation of a novel self-sealing chewable sustained release tablet that can maintain controlled release of drug regardless of compaction, crushing, or chewing. The new formulation contains polyethylene oxide which produces a sealant effect for cracks produced in the polymer coating during compaction. Dissolution studies were conducted and...

Resource Type:

Dissertation

Full Text:

Oral Formulations, (3) A Novel Zero Order Release Matrix Tablet. Abstract approved James W This
Development of Hot-melt Pan-coating, Application to Sustained-release Capsules and Tamper Resistant-coating. 2) Formulation of Verapamil HCl and Diltiazem HCl Semisolid Matrix Capsules. 3) Novel Sustained Release Tablet of Glipizide: Compression of Coated Drug Beads, Formulation, Dissolution, and Convolution. 4) Verapamil Sustained Release: New Formulation and Convolution

Creator:

Nguyen, Chien Ngoc

Abstract:

Hot-melt pan-coating, which is a novel coating method and takes 2-3 hours for 300 mg coating weight gain per capsule and tamper-resistant coating, which takes 30 minutes, is much faster than tedious sugar coating and allows greater coating weight gains in shorter times than spray-melt coating. Although hot-melt pan coating...

Resource Type:

Dissertation

Full Text:

approved: James W. Ayres J. Mark Christensen Hot-melt pan-coating, which is a novel

ScholarsArchive@OSU

A novel self-sealing chewable sustained release tablet of acetaminophen ; Development and evaluation of novel itraconazole oral formulations ; A novel zero order release matrix tablet

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