Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Creator Magnusson, K. Committee Member Magnusson, Kathy R. Subject Gastrointestinal system -- Immunology

The effect of dietary compounds on human cathelicidin antimicrobial peptide gene expression mediated through farnesoid X receptor and its potential role in gastrointestinal health

Creator:

Campbell, Yan

Abstract:

The human cathelicidin antimicrobial peptide (CAMP) is a broad spectrum microbicidal agent and modulator of both the innate and adaptive immune system. It is induced by 1,25-dihydroxyvitamin D (1,25(OH)₂D₃) through activation of the vitamin D receptor (VDR) and primary bile salts through activation of the xenobiotic nuclear receptor farnesoid X...

Resource Type:

Dissertation

Full Text:

Karplus and Dr. Kathy Magnusson. I thank Dr. Andy Karplus for your patience in answering my numerous