Index Catalog // ScholarsArchive@OSU

Activation, incorporation and modification of capreomycidine during viomycin biosynthesis

Creator:: Fei, Xiaobo
Abstract:: Molecular genetic and enzymological techniques have been employed to study antibiotic biosynthesis. The nonproteinogenic amino acid capreomycidine is the signature residue found in the tuberactinomycin family of antitubercular peptide antibiotics and an important element of the pharmacophore. Recombinant VioG, a single module peptide synthetase from the viomycin gene cluster cloned...
Resource Type:: Masters Thesis
Full Text:: . Maier, and Dr. Rockey for their guidance and assistance throughout my graduate studies. I would like

Application of modern NMR techniques to structure elucidation of bioactive natural products from tunicates

Creator:: Sikorska, Justyna
Abstract:: Recent developments in NMR hardware have extended the reach of natural products chemists to structure elucidation of compounds isolated on a nanomolar scale. In parallel with advances in hardware new NMR techniques for structure elucidation have evolved, e.g. quantitative NOEs, residual dipolar couplings (RDCs)and diffusion-ordered spectroscopy (DOSY). The application of...
Resource Type:: Dissertation

Mitochondrial decay in the aging rat heart : changes in fatty acid-supported bioenergetics and macromolecular organization of the electron transport system

Creator:: Gómez Ramirez, Luis A.
Abstract:: Decline in cardiac pump function is a hallmark of aging where mitochondrial decay is an important underlying cause. Although certainly multifactorial in nature, both dysfunction of the machinery involved in the chemiosmotic process of energy transduction and lower capacity to maintain fatty acid-driven respiration are identified as intrinsic factors of...
Resource Type:: Dissertation
Full Text:: research committee, Drs. Claudia S. Maier, Balz Frei, Joseph Beckman and Adam Higgins not only for

Molecular origins of peptide entrapment in polyethylene oxide layers

Creator:: Wu, Xiangming
Abstract:: A more quantitative understanding of peptide entrapment and elution from otherwise protein-repellent polyethylene oxide (PEO) brush layers will provide direction for development of new strategies for drug storage and delivery. Here we describe criteria for peptide integration and structural change within the PEO brush, and discuss the reversibility of peptide...
Resource Type:: Dissertation
Full Text:: McPhail, Dr. Victor Hsu and Dr. Claudia Maier for all the valuable discussion about my research and for

Improving in vitro mineral nutrition for diverse red raspberry and Rubus germplasm

Creator:: Poothong, Sukalya
Abstract:: Red raspberry, Rubus idaeus L., is a valuable crop for the U.S. Pacific Northwest and clonal propagation is required to produce disease-free plants and for germplasm preservation. One challenge of red raspberry micropropagation is the wide variation in growth response among the cultivars. The studies described in this dissertation were...
Resource Type:: Dissertation
Full Text:: . Milligan, Prof. Claudia S. Maier, and Prof. Thomas Chastain for knowledgeable encouragement, assistance

Continuous monitoring and modeling to assess pesticide exposure in critical habitat for Pacific salmonids

Creator:: Janney, Philip K.
Abstract:: Pacific Northwest and California freshwater resources are key elements in the life history and ecology of Pacific salmon and steelhead listed as threatened or endangered under the Endangered Species Act. Risk to listed Pacific salmonid species can be assessed by evaluating the spatial and temporal co-occurrence of salmonid species at...
Resource Type:: Dissertation
Full Text:: , and Dr. Claudia Maier for sticking with me over the years. I would like to thank all of the members

Carbon Nanodots as Biolabels for Fluorescence Immunoassays

Creator:: Wu, Yuanyuan
Abstract:: There has been a tremendous growth in interest in carbon nanodots (C-dots) in the past several years. As a nascent nanomaterial, C-dots have shown great promise in applications that benefit from their superior water dispersibility, low toxicity, non-blinking fluorescent output, chemical and biological compatibility, ease of functionalization and resistance to...
Resource Type:: Dissertation
Full Text:: thank my thesis committee, Dr. Christopher. M. Beaudry, Dr. Claudia Maier, Dr. Joseph. W. Nibler, Dr

Centrifugal Partition Chromatography, Microfabrication, and a Smartphone-based Detection Platform : Analytical Chemistry from Preparative-scale Separation to Micro-scale Analysis

Creator:: Boonloed, Anukul
Abstract:: Analytical chemistry is an area of chemistry primarily focused on the study and use of instruments for separation, identification, and quantification of an analyte of interest. Specifically, separation science within analytical chemistry often refers to the process of dividing mixtures into their small component parts based on differences in their...
Resource Type:: Dissertation
Full Text:: thesis committee members, Dr. Staci L. Simonich, Dr. Claudia S. Maier, Dr. Dipankar Koley, Dr. Jeffrey

CoLocalized Excitation Emission Resolution : A CLEER approach for multicolor fluorescence analysis

Creator:: Almlie, C. Kyle
Abstract:: Fluorescence has proven to be a robust and powerful method of analysis in numerous fields: forensics, pharmaceutics, geology, food science, and environmental sciences have all developed a large collection of fluorescence instruments and methods to overcome application-specific challenges. Biological applications saw the same development of a fluorescence toolkit with methods...
Resource Type:: Dissertation

Transcriptomic approaches for discovering regenerative and developmental regulatory networks in zebrafish

Creator:: Garland, Michael A.
Abstract:: Zebrafish are capable of fully regenerating organs and tissue such as their caudal fin, which is similar to a human regrowing an arm or a leg. In contrast, most mammals including humans have a greatly reduced capacity for wound healing. The ability of zebrafish to undergo this regenerative process, called...
Resource Type:: Dissertation
Full Text:: . Claudia Maier, who jumped in at the last minute as Graduate Council Representative and offered new

ScholarsArchive@OSU

Activation, incorporation and modification of capreomycidine during viomycin biosynthesis

Application of modern NMR techniques to structure elucidation of bioactive natural products from tunicates

Mitochondrial decay in the aging rat heart : changes in fatty acid-supported bioenergetics and macromolecular organization of the electron transport system

Molecular origins of peptide entrapment in polyethylene oxide layers

Improving in vitro mineral nutrition for diverse red raspberry and Rubus germplasm

Continuous monitoring and modeling to assess pesticide exposure in critical habitat for Pacific salmonids

Carbon Nanodots as Biolabels for Fluorescence Immunoassays

Centrifugal Partition Chromatography, Microfabrication, and a Smartphone-based Detection Platform : Analytical Chemistry from Preparative-scale Separation to Micro-scale Analysis

CoLocalized Excitation Emission Resolution : A CLEER approach for multicolor fluorescence analysis

Transcriptomic approaches for discovering regenerative and developmental regulatory networks in zebrafish

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