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Filtering by: Creator Cooper, Ranessa L. Committee Member Manchanda, Aayushi Degree Level Bachelor's

Characterization of Ferlin-1-Like 6 (Fer1L6) Through Lipid Membrane Interactions

Creator:

Matlapudi, Susmitha

Abstract:

The ferlin protein family regulates membrane trafficking events for a wide range of cellular and physiological processes in eukaryotic organisms. Structurally, ferlins are distinguished by containing five to seven C2 domains with a single-pass transmembrane domain at the C-terminus. In mammals, there are 6 ferlin genes, including Fer1L6, which confer...

Resource Type:

Honors College Thesis

Full Text:

vesicles during the transition from myoblasts to myofibers (Lek, Evesson, Sutton, North & Cooper, 2012
Cloning the zebrafish otoferlin b wildtype and a transmembrane mutant to characterize changes in cellular localization

Creator:

France, Rebecca A.

Abstract:

Otoferlin is a protein that is essential in the process of hearing. Mutations in otoferlin are associated with profound recessive deafness. The long-term goal of the Johnson lab is to understand how otoferlin contributes to hearing and why certain mutations result in deafness. This project sought to characterize the difference...

Resource Type:

Honors College Thesis

Full Text:

., Sophocleous, R. A., Turnbull, L., Whitchurch, C. B., & Cooper, S. T. (2016). Ferlins Show Tissue‐Specific