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Filtering by: Has journal ECS Journal of Solid State Science and Technology Remove constraint Has journal: ECS Journal of Solid State Science and Technology Committee Member McGuire, Joseph Remove constraint Committee Member: McGuire, Joseph Degree Field Chemical Engineering Remove constraint Degree Field: Chemical Engineering

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Improving the post-thaw processing of cryopreserved red blood cells using a combined approach of mathematical modeling and microfluidics

Creator:

Lusianti, Ratih E.

Abstract:

This study lays the groundwork on potential techniques that could be employed to improve the post-thaw wash processing of cryopreserved human red blood cells. Transfusion of red blood cells is one of the most commonly practiced procedures in clinical medicine. Millions of red blood cell units are transfused to patients...

Resource Type:

Dissertation

Full Text:

you to Oregon State University and the National Science Foundation for financially supporting this
Removal of cryoprotectant with the use of a microseparation device

Creator:

Lusianti, Ratih E.

Abstract:

Cryoprotectants (CPAs) such as glycerol and dimethyl sulfoxide (DMSO) are commonly used during cryopreservation of cell based therapeutics. Although these additives are beneficial during freezing, it is often desirable to remove them before infusion into a patient. Currently, the most common method for CPA removal is by centrifugation. This method...

Resource Type:

Masters Thesis

Full Text:

, the water content in the aqueous solution will favor the solid state and begin to form ice crystals
Dynamic simulation of drying and quality changes during malt kilning

Creator:

Coonce, Vincent M.

Abstract:

The principal aim of this study was the use and evaluation of dynamic modeling techniques to identify mathematical models for cereal drying rates and quality changes that best describe thin-layer malt drying data. Seven thin-layer malt drying experiments were performed at the Great Western Malting pilot facilities, Vancouver, WA. Malt...

Resource Type:

Masters Thesis

Full Text:

of Master of Science in Chemical Engineering and Food Science and Technology presented on January
An investigation of multiphase flow in complex microchannel geometries for hemodialysis systems using residence time distribution analysis

Creator:

Coblyn, Matthew Y.

Abstract:

There are approximately 2.2 million cases of End-stage Renal Disease (ESRD) worldwide and current hemodialysis treatment is costly and ultimately insufficient compared to kidney transplantation. There is a strong need to arrive at a better solution for treating ESRD. Microchannel-based hemodialysis is one proposed option, already shown to have improved...

Resource Type:

Dissertation

Full Text:

be a part of the field of science and engineering. Thank you, Patrick McNeff and Dusty Ward, for
Heparin-regulated release of growth factors in vitro and angiogenic response in vivo to implanted hyaluronan hydrogels containing VEGF and bFGF

Creator:

Pike, Daniel B.

Abstract:

Biocompatible hydrogels composed of covalently crosslinked, chemically modified hyaluronan (HA), gelatin (Gtn), and heparin (Hp) were synthesized for controlled release of human vascular endothelial growth factor (VEGF) or basic fibroblast growth factor (bFGF). We hypothesized that inclusion of small quantities of heparin in these gels would result in regulated growth...

Resource Type:

Masters Thesis

Full Text:

(EB004514), and by Oregon State University, and in part by a Centers of Excellence award from the state
Functional polymers and proteins at interfaces

Creator:

Schilke, Karl F.

Abstract:

Functional polymers and proteins at interfaces and surfaces are of fundamental importance for biomaterials, biocatalysis and microreactor applications. Candida antarctica lipase B immobilized on poly-DL-tryptophan tethers showed 30x higher specific activity in aqueous and non-aqueous media than the same enzyme adsorbed or covalently bound directly to the surface. An excess...

Resource Type:

Dissertation

Full Text:

methods for solid-supported enzymatic reactions and production and characterization of surface coatings
Optimization of cryoprotectant addition and removal procedures for vitrification of adherent mammalian cells

Creator:

Fry Davidson, Allyson

Abstract:

Cryopreservation of adherent cells may be advantageous for cell types that are difficult to preserve in suspension or when it is necessary to preserve characteristics of the adherent cultured cells. Vitrification is a promising procedure for the preservation of adherent cells that prevents ice crystal formation and the resulting dissociation...

Resource Type:

Dissertation

Full Text:

. Title: Optimization of Cryoprotectant Addition and Removal Procedures for Vitrification of Adherent
Membrane permeability properties of human granulocytes

Creator:

Vian, Alexander M.

Abstract:

In the last decade, there has been renewed interest in the use of granulocyte transfusions to treat infections in individuals with compromised immune systems. However, granulocytes only remain functional for about a day after isolation and this short shelf life is a significant drawback. Cryopreservation would allow long term storage...

Resource Type:

Masters Thesis

Full Text:

with S180. The solid tumors that had formed regressed by necrosis and Page 8 of 48 eventually
Photoluminescence properties investigation of germanium inserted biosilica generated by bioreactor culture of marine diatom Nitzschia frustulum

Creator:

Qin, Tian

Abstract:

The purpose of this research was to investigate the optoelectronic properties of the Ge doped biosilica, mainly focused on the photoluminescence (PL) properties of diatom frustules of N. frustulum that contain metabolically inserted germanium oxide produced by a two-stage photobioreactor cultivation process. In order to explain the observed PL intensity...

Resource Type:

Masters Thesis

Full Text:

ABSTRACT OF THE THESIS OF Tian Qin for the degree of Master of Science in Chemical Engineering
Synthesis and function of bioactive, block copolymer surfactant constructs as relevant to the preparation of anticoagulant and antibacterial medical implant surfaces.

Creator:

Joshi, Pranav R.

Abstract:

Nisin, an antibacterial peptide proven to be an effective inhibitor of Gram-positive bacteria, was incorporated into novel block copolymer constructs and tested for retained antibacterial activity. Covalent coupling was achieved by chemical modification of the N-terminal isoleucine to introduce a thiol group. Thiolated nisin derivatives were then linked to poly[ethylene...

Resource Type:

Dissertation

Full Text:

to Dr. Tom Shellhammer at the Department of Food Science and Technology, for help with Zeta

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Academic Affiliation

Chemical, Biological and Environmental Engineering9
Chemical Engineering2
Food Science and Technology1

Advisor

Higgins, Adam2
Higgins, Adam Z.2
Peattie, Robert A.2
Jovanovic, Goran N.1
Kelly, Christine1
more Advisors »

Commencement Year

Commencement Year range begin – Commencement Year range end

Current results range from 1993 to 2018

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Committee Member

McGuire, Joseph[remove]12
Field, Jennifer2
Jovanovic, Goran2
Liu, Hong2
Penner, Michael2
more Committee Members »

Creator

Lusianti, Ratih E.2
Coblyn, Matthew Y.1
Coonce, Vincent M.1
Daalkhaijav, Uranbileg1
Edgar, Erik S.1
more Creators »

Date

Date range begin – Date range end

Current results range from 1991 to 2018

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Decade

2010-20196
2000-20095
1990-19991

Degree Field

Chemical Engineering[remove]12

Degree Level

Doctoral6
Master's6

Degree Name

Doctor of Philosophy (Ph.D.)6
Master of Science (M.S.)6

File Format

application/pdf2

Language

English [eng]12

License

All rights reserved11

Non-Academic Affiliation

Oregon State University. Graduate School11

Peer Reviewed

No11

Resource Type

Dissertation6
Masters Thesis6

Rights Statement

In Copyright11
Copyright Not Evaluated1

Subject

Blood cells -- Cryopreservation2
Glycerin2
Heparin2
Separation (Technology)2
Abdominal aneurysm -- Prevention1
more Subjects »

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