Index Catalog // ScholarsArchive@OSU

Nisin adsorption to PEO-PPO-PEO tri-block copolymer layers and its resistance to elution by fibrinogen

Creator:: Ryder, Matthew P.
Abstract:: While hydrophobic surfaces coated with the poly[ethylene oxide]-poly[propylene oxide]-poly[ethylene oxide] (PEO-PPO-PEO) surfactant Pluronic® F108 are highly resistant to plasma protein adsorption, the antimicrobial peptide nisin has been observed to adsorb in multilayer quantities at such surfaces, and the PEO chains themselves suggested to inhibit nisin exchange by blood proteins. But...
Resource Type:: Masters Thesis
Full Text:: approved: ________________________________________________________________________ Joseph McGuire

Synthesis and function of bioactive, block copolymer surfactant constructs as relevant to the preparation of anticoagulant and antibacterial medical implant surfaces.

Creator:: Joshi, Pranav R.
Abstract:: Nisin, an antibacterial peptide proven to be an effective inhibitor of Gram-positive bacteria, was incorporated into novel block copolymer constructs and tested for retained antibacterial activity. Covalent coupling was achieved by chemical modification of the N-terminal isoleucine to introduce a thiol group. Thiolated nisin derivatives were then linked to poly[ethylene...
Resource Type:: Dissertation
Full Text:: : _____________________________________________________________________ Joseph McGuire Nisin, an antibacterial peptide proven to be an effective inhibitor of Gram

Evaluation of Topical Application of 1% Morphine Sulfate Solution as an Analgesic on the Healthy Equine Eye

Creator:: Gordon, Emma
Abstract:: Corneal ulcers are one of the most common eye conditions of the horse, with potentially serious complications such as loss of vision or the eye itself. They are extremely painful due to the large number of sensory nerve endings found in the cornea. Horses frequently show signs of ophthalmic pain...
Resource Type:: Masters Thesis
Full Text:: W. Schlipf Jr. Abstract: Corneal ulcers are one of the most common eye conditions of the horse

A force plate for measuring contact forces during dependent transfers onboard aircraft

Creator:: Schafer, Christopher A.
Abstract:: The transfer of air travelers with disabilities between a mobility aid and an aircraft seat is a major source of injury for both the travelers and the airline personnel assisting in the transfer. The risk to both parties might be reduced through the biomechanical study of the transfer task. Such...
Resource Type:: Masters Thesis
Full Text:: . Joseph R. Zaworski The transfer of air travelers with disabilities between a mobility aid and an

Lead(II) Extraction with Electrospun Spiropyran Functionalized PMMA Nanofibers

Creator:: Fuchs, Brian K.
Abstract:: A system to reversibly extract Pb²⁺ ions from aqueous solutions using spiropyran functionalized nanofibers was proposed. Spiropyrans are photochromic compounds which undergo a conformational change that alters their physical properties and makes Pb²⁺ binding possible upon irradiation with UV light (365 nm). Irradiation with green light (525 nm) reverses this...
Resource Type:: Honors College Thesis
Full Text:: assistance, technical support, and encouragement in pursuing new ideas. Dr. Joseph McGuire for being a

Preliminary study on the effect of pH on the treatment of lead contaminated wastewaters with ozone

Creator:: Adolf, Ronald L.
Abstract:: Ozone was found to quickly reduce the concentration of lead in a prepared solution when the solution pH of said solution was greater than 7.0. When a solution having a pH of greater than 7.0 was filtered the concentration of lead was less than approximately 1.0 ppm. 1.0 ppm is...
Resource Type:: Masters Thesis
Full Text:: . Joseph McGuire for serving on my graduate committee. Special thanks to A+ Computers and my father

Immobilization of hen egg white lysozyme by the sole histidine residue to polystyrene beads through peptide spacers

Creator:: Wu, Yawen
Abstract:: Lysozyme is a natural antimicrobial agent that is effective against many food spoilage and pathogenic microorganisms by disintegrating their cell walls. Immobilization of lysozyme has attractive applications for use in the food industry: (1) The enzyme could be readily separated from treated foods and beverages and re-used while the foods...
Resource Type:: Dissertation
Full Text:: also extended to: Professor Floyd Bodyfelt, Dr. Joseph McGuire, Dr. Ronald Wrolstad, Dr. Mina

Heparin-regulated release of growth factors in vitro and angiogenic response in vivo to implanted hyaluronan hydrogels containing VEGF and bFGF

Creator:: Pike, Daniel B.
Abstract:: Biocompatible hydrogels composed of covalently crosslinked, chemically modified hyaluronan (HA), gelatin (Gtn), and heparin (Hp) were synthesized for controlled release of human vascular endothelial growth factor (VEGF) or basic fibroblast growth factor (bFGF). We hypothesized that inclusion of small quantities of heparin in these gels would result in regulated growth...
Resource Type:: Masters Thesis
Full Text:: Gtn (50:50 w/w) with 0-3% heparin (w/w relative to total HA or HA-Gtn content). Either VEGF or bFGF

Removal of cryoprotectant with the use of a microseparation device

Creator:: Lusianti, Ratih E.
Abstract:: Cryoprotectants (CPAs) such as glycerol and dimethyl sulfoxide (DMSO) are commonly used during cryopreservation of cell based therapeutics. Although these additives are beneficial during freezing, it is often desirable to remove them before infusion into a patient. Currently, the most common method for CPA removal is by centrifugation. This method...
Resource Type:: Masters Thesis
Full Text:: 10% w/v glycerol solution .……………………..……………………………………....…………….. 44 5.3 Hydraulic permeability

Squeeze-off & gel patch repair methods for polyethylene pipe in natural gas distribution lines

Creator:: Harris, Kevin E.
Abstract:: The natural gas industry has become essential in many areas in the United States. Currently there is over 37.5 million miles of natural gas distribution lines. A large majority of these lines are polyethylene pipes. With such a large percentage of polyethylene lines in use gas companies are continually looking...
Resource Type:: Masters Thesis
Full Text:: -0.1 0 70 80 90 100 110 120 130 140 Temp (°C) R ev H ea t F lo w (W /g ) MDPE-decalin HDPE

ScholarsArchive@OSU

Nisin adsorption to PEO-PPO-PEO tri-block copolymer layers and its resistance to elution by fibrinogen

Synthesis and function of bioactive, block copolymer surfactant constructs as relevant to the preparation of anticoagulant and antibacterial medical implant surfaces.

Evaluation of Topical Application of 1% Morphine Sulfate Solution as an Analgesic on the Healthy Equine Eye

A force plate for measuring contact forces during dependent transfers onboard aircraft

Lead(II) Extraction with Electrospun Spiropyran Functionalized PMMA Nanofibers

Preliminary study on the effect of pH on the treatment of lead contaminated wastewaters with ozone

Immobilization of hen egg white lysozyme by the sole histidine residue to polystyrene beads through peptide spacers

Heparin-regulated release of growth factors in vitro and angiogenic response in vivo to implanted hyaluronan hydrogels containing VEGF and bFGF

Removal of cryoprotectant with the use of a microseparation device

Squeeze-off & gel patch repair methods for polyethylene pipe in natural gas distribution lines

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