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Filtering by: Advisor Sun, Bo Remove constraint Advisor: Sun, Bo Committee Member McIntyre, David Remove constraint Committee Member: McIntyre, David License All rights reserved Remove constraint License: All rights reserved

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  • Multicellular monolayer’s self-organization under external stimuli

    Creator:
    Li, Guanyu
    Abstract:
    Cell signaling under external stimulation is a critical mechanism that governs many biological processes such as cell proliferation, cell migration, and cell apoptosis, etc. For multicellular organisms, the ability to synchronize heterogeneous individual cellular responses through intercellular communication is crucial to maintain normal functionality. However, even though the biological pathways...
    Resource Type:
    Dissertation
    Full Text:
    Monolayer’s Self-organization Under External Stimuli Abstract approved: Bo Sun Cell signaling under

  • Multi-scale Investigation of Bidirectional Feedback Mechanism Between Breast Cancer Cells and Extracellular Matrix

    Creator:
    Kim, Jihan
    Abstract:
    Cell migration is fundamental for physiological processes such as immune re-sponses, wound healing and development. It is also a critical characteristic of metastatic cancer cells. An extensive amount of studies have focused on 2D sub-strates in order to understand the mechanism of cancer metastasis. However, much less is known about...
    Resource Type:
    Dissertation
    Full Text:
    thank my adviser Bo Sun who guided me through this wonderful PhD journey. He has not only been my

  • Mechanics of three-dimensional microenvironments of cells

    Creator:
    Jones, Christopher
    Abstract:
    The structure and mechanics of tissues affect many important cellular functions such as migration, differentiation, and growth. Mechanical interactions between cells and the extracellular matrix (ECM), as well as ECM-mediated mechanical communication between cells, plays a part in coordinating collective cellular dy- namics during critical processes such as morphogenesis, tissue...
    Resource Type:
    Dissertation
    Full Text:
    -Dimensional Microenvironments of Cells Abstract approved: Bo Sun The structure and mechanics of tissues