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  • Innovative Bioanalytical Tools & Methods for Combinatorial Non-Coding RNA Analysis

    Creator:
    Zhang, Lulu
    Abstract:
    Recently researchers have discovered that groups of small non-coding RNAs (ncRNAs) play regulatory roles in gene expression and participate in various biological processes. For example, pathogenesis of many diseases, cell cycle regulation, and signaling pathways. Intracellular and live cell imaging of small ncRNA groups will reveal their relative expression levels...
    Resource Type:
    Dissertation
    Full Text:
    - transcriptionally, during messenger-RNA translation.10 Current nucleic-acid-based in situ sensors that are

  • Bridging the Gap Between Equilibrium Properties and Ultrafast Dynamics with Time-Resolved Spectroscopy of Functional Systems

    Creator:
    Krueger, Taylor D.
    Abstract:
    Ultrafast spectroscopy has recently gained momentum as a powerful, noninvasive characterization toolset capable of studying a diverse array of samples with applications in chemistry, physics, biology, engineering, and more. Two popular ultrafast spectroscopic techniques include femtosecond transient absorption (fs-TA) and femtosecond stimulated Raman spectroscopy (FSRS). The latter of these techniques...
    Resource Type:
    Dissertation
    Full Text:
    transient absorption (fs-TA) and femtosecond stimulated Raman spectroscopy (FSRS). The latter of these

  • Generation of narrowband THz pulses and THz studies of ultrafast phenomena in semiconductor quantum wells

    Creator:
    Danielson, Jeremy R.
    Abstract:
    This work comprises two main parts: creating and shaping narrowband, pulsed THz radiation in a table-top optical setup; and applying THz pulses to semiconductor nanostructures to study electron dynamics. I developed a scheme to shape the THz output of a fanned-out periodically poled lithium niobate (PPLN) crystal. The pulses are...
    Resource Type:
    Dissertation
    Full Text:
    efficiencies as high as 4 ä 10 -6 . Using a Michelson interferometer, the THz field autocorrelation was also

  • Optical Development and Materials Applications of Tunable Femtosecond Stimulated Raman Spectroscopy

    Creator:
    Zhu, Liangdong
    Abstract:
    To obtain a mechanistic understanding of the chemical processes, techniques that offer a frame-by-frame visualization of molecular structure during a reaction are of vital importance. Numerous efforts and advances have been made in order to acquire such vivid molecular “movies”, especially in the electronic excited state. Ultrafast molecular spectroscopy method...
    Resource Type:
    Dissertation
    Full Text:
    band while does not require the use of ultrashort pulses below 10 fs for instance. 4 1.2

  • Light-matter interactions : from the photophysics of organic semiconductors to high spatial resolution optical tweezer-controlled nanoprobes

    Creator:
    Kendrick, Mark J.
    Abstract:
    Studies of light-matter interactions in organic semiconductors and in optical tweezer trapping of nanoparticles are presented. In the research related to organic semiconductor materials, a variety of novel materials and their composites have been characterized, and physical mechanisms behind their optoelectronic properties have been established. Three novel functionalized hexacene derivatives...
    Resource Type:
    Dissertation
    Full Text:
    charge carrier recombination, which led to a factor of 5-10 increase in continuous wave photocurrents

  • Nonlinear terahertz spectroscopy of carbon nanomaterials and semiconductor nanostructures

    Creator:
    Paul, Michael Jason
    Abstract:
    This thesis will cover my work relating to the developing field of terahertz (THz) science and technology. It will present experimental and theoretical studies investigating the optical and electrical properties of various material systems using novel THz imaging and spectroscopy techniques. Due to its low photon energy, THz imaging and...
    Resource Type:
    Dissertation
    Full Text:
    . The fields are strong enough to generate high density free carriers (Ne > 10 17 cm−3) via high-energy

  • High efficiency delta-sigma modulation data converters

    Creator:
    Lee, Kyehyung
    Abstract:
    Enabled by continued device scaling in CMOS technology, more and more functions that were previously realized in separate chips are getting integrated on a single chip nowadays. Integration on silicon has opened the door to new portable wireless applications, and initiated a widespread use of these devices in our common...
    Resource Type:
    Dissertation
    Full Text:
    drivers for the headphones. The digital filter increases the sampling rate from fs = 48 kHz to 64·fs

  • Receiver synchronization for UWB TDOA localization

    Creator:
    Baek, Seungjin
    Abstract:
    Pulsed ultra-wideband (UWB) radio uses extremely short pulses to transmit information. Such pulses provide very fine timing information, which has led to technological advances in high-precision localization. This thesis investigates UWB localization strategies with a focus on receiver synchronization algorithms for time-difference-of-arrival localization to achieve centimeter accuracies in a 3-dimensional...
    Resource Type:
    Masters Thesis
    Full Text:
    Arrival . . . . . . . . . . . . . . . . . . . 10 2.2 Existing Synchronization Algorithms for TDOA

  • On the photoresponse of several novel oligoacene and anthradithiophene derivatives

    Creator:
    Day, Jonathan
    Abstract:
    The results of an investigation into carrier dynamics in several novel functionalized and solution-processable pentacene and anthradithiophene derivatives are reported. Measurements were made of real-time photoresponse of polycrystalline thin films of these materials to ultrafast laser pulses, on picosecond to microsecond time-scales, as well as measurements of dark current and...
    Resource Type:
    Dissertation
    Full Text:
    . . . . . . . . . . . . . 10 1.9 ADT-TIPS-F π-stacking (top) contrasted with that of ADT-TES-F (bottom). (From S. Subramanian

  • Coulomb Explosion in Moderately Intense Nanosecond Laser Fields

    Creator:
    Yao, Yuzhong
    Abstract:
    In this dissertation, I present experimental observations of multiply charged atomic ions (MCAI) generated from interactions of atomic/molecular clusters with moderately intense nanosecond laser pulses. This process is also known as Coulomb explosion (CE) and it has been extensively studied in intense laser fields using ultrashort pulses. Several prevailing theories...
    Resource Type:
    Dissertation
    Full Text:
    quantum confinement and boundary effects.10 Uncommon structures of clusters lead to changes in the gap