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Filtering by: Creator Moore, Paul Harris Committee Member McPhail, Kerry Degree Field Pharmaceutical Sciences

Detection, biosynthesis, and structural investigations of naturally occurring alkynes and other microbial metabolites

Creator:

Back, Daniel C.

Abstract:

Natural products have long been an important source of resources for humans. Many of these compounds possess unique chemical structures and potent biological properties. By targeting natural products with specific chemical properties, we can gain a better understanding of the roles these compounds play in the environment and their interactions...

Resource Type:

Dissertation
Non-viral Vectors for Ocular Gene Delivery

Creator:

Herrera-Barerra, Marco, F.

Abstract:

Nucleic acid therapeutics has cemented itself as one of the most efficacious and robust avenues for treatment of a wide range of diseases from vaccine development to treatment of liver, retina, cancer applications. Non-viral mediated gene delivery using lipid-based nanoparticle (LNP) carriers has proven its compatibility with addressing unexpected, fast...

Resource Type:

Dissertation

Full Text:

, but above all selfless mentoring. Madre, Nari, Juliana, Paul, Ros, Abe, Madeleine, Abhijeet, Luz
Natural Products as Pharmacological Tools to probe Mitochondrial and Secretory Function in Cancer Cells

Creator:

Wan, Xuemei

Abstract:

Cancer is the second leading cause of death in the United States. To date, over 60% of current anticancer drugs were inspired by the discovery of chemical structure from nature, commonly known as a natural product. This work represents the biological characterization of several marine natural product compounds and their...

Resource Type:

Dissertation