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Filtering by: Creator Romero-Canyas, Rainer Committee Member Mehl, Ryan

Viral Targeting of Host Hubs: Interactions between the Rabies Virus and LC8

Creator:

Jespersen, Nathan E.

Abstract:

As obligate intracellular parasites, viruses rely on host machinery for their own reproduction. Viruses are therefore required to interact with a wide variety of host proteins, despite limitations in viral genome size. The most parsimonious method of success is to hijack central and essential proteins, known as hub proteins. LC8...

Resource Type:

Dissertation
Structural Insights into Novel Sugar Phosphate Cyclases and Flavoenzymes

Creator:

Kean, Kelsey M.

Abstract:

The function of a protein is defined by its three-dimensional structure, and in understanding the three-dimensional structure of a protein, we gain an understanding of its function and mechanism. Protein structures, especially at high resolution, can provide detailed insights into many elements of enzyme function and catalysis – identifying residues...

Resource Type:

Dissertation