Index Catalog // ScholarsArchive@OSU

An assessment of the cardiac toxicity of compounds that cause methemoglobinemia using a non-vascularized fish heart model

Creator:: Nichols, John W.
Abstract:: Non-vascularized hearts of buffalo sculpin (Enophrys bison) were used to investigate the cardiac toxicity of compounds that cause methemoglobinemia. The affinity of sculpin cardiac myoglobin for oxygen (P50 = 1.10 torr at 20 C°, pH 7.8) was lower than that of mammals studied (P50 = .44 and .76 torr for...
Resource Type:: Dissertation
Full Text:: -Vascularized Fish Heart Model Abstract approved: Redacted for Privacy (d/Lavern J. Weber Non-vascularized

Progress Towards the Total Synthesis of Bazzanin K

Creator:: Salvo, Patrick
Abstract:: Molecular chirality plays a critical role in chemistry, biology, and medicine. To study and better understand conformational chirality, it is necessary to obtain structurally interesting molecules that exhibit this form of chirality. Our lab utilizes total synthesis and methodological development to obtain conformationally chiral natural products of interest. We believe...
Resource Type:: Masters Thesis
Full Text:: . Chim. Pays-Bas., 1899, 18, 457. 4 C. J. Brown, and A. C. Farthing, Nature, 1949, 164, 915—916

Structural effects on enzymatic activity of bacteriophage T4 lysozyme upon adsorption to colloidal silica

Creator:: Xu, Qiurong, 1964-
Resource Type:: Masters Thesis
Full Text:: and support. I am grateful to Dr. Gary Merrill, Dr. Michelle Bothwell, and Dr Yim Solomon for kindly

Search for protein-protein interactions underlying the cis-preferential replication of turnip yellow mosaic virus

Creator:: Wallace, S. Ellen
Abstract:: Coreplication experiments have revealed that replication of turnip yellow mosaic virus (TYMV) RNA in turnip protoplasts is cis-preferential. Genomes encoding mutant p141 or p66, proteins essential for virus replication, were inefficiently rescued by a helper genome. One model for the cis-preferential replication of TYMV is that p66 and p141 form...
Resource Type:: Masters Thesis
Full Text:: members of my committee, Gary Merrill, Lyle Brown and Lloyd Swanson. The assistance of Kay Bransom and

Proteoglycans in the inner limiting membrane and their influence on axonal behavior in embryonic chicken retina

Creator:: Chai, Lin
Resource Type:: Dissertation
Full Text:: members Christopher J. Bayne, Frank L. Moore, Gary Merrill, and Alfred R. Menino for serving on my

Molecular mechanisms of peroxisome proliferator-activated receptor signaling

Creator:: Dowell, Paul T.
Abstract:: Peroxisome proliferator-activated receptors (PPARs) are members of a large group of ligand-regulated transcription factors that includes nuclear receptors for steroid and thyroid hormones, retinoids and vitamin D₃. Synthetic fibrates and thiazolidinediones that bind to and activate PPARs are used efficaciously in humans to remedy hypertriglyceridemia and non-insulin dependent diabetes mellitus,...
Resource Type:: Dissertation
Full Text:: members of my graduate committee, Dr. Paul Franklin, Dr. Terri Lomax, Dr. Gary Merrill and Dr. Anthony

Genetic aspects of sulfite tolerance in Saccharomyces cerevisiae

Creator:: Avram, Dorina
Resource Type:: Dissertation
Full Text:: the manuscripts and my thesis. I thank Dr. Gary Merrill for being such a fine mentor, for his

In vivo detoxification of acetic acid in Saccharomyces cerevisiae

Creator:: Ding, Jun
Abstract:: The studies described in this thesis were motivated by ongoing efforts to develop lignocellulosic biomass as an efficient and practical source of renewable energy. Enormous problems complicate these efforts to reduce reliance on greenhouse gas-generating fossil fuels. Simply obtaining the fermentable sugars available in the cellulose and hemicellulose components of...
Resource Type:: Dissertation
Full Text:: . I would also like to thank my committee members, Dr. Gary Merrill, Dr. Mike Penner, Dr. Michael

Analysis of ras gene mutations in rainbow trout tumors

Creator:: Chang, Yung-jin
Abstract:: For ras gene mutation analysis in the rainbow trout (Oncorhynchus mykiss) model system, a partial trout ras sequence was identified using the polymerase chain reaction (PCR). Two synthetic oligonucleotides based on rat K-ras gene sequence were used as primers for the PCR procedure. A 90 base pair (bp) sequence, referred...
Resource Type:: Dissertation
Full Text:: , Gary Merrill, David Barnes, George Pearson, Lawrence Curtis. And other professors, Jerry Hendricks

Genetic and phenotypic variation associated with the resistance gene SOD1 in Biomphalaria glabrata, an important intermediate host of Schistosomiasis

Creator:: Bonner, Kaitlin M.
Abstract:: Schistosomiasis afflicts 200 million people and is responsible for 200,000 deaths per year. The infection is caused by a digenean trematode in the genus Schistosoma. The parasite must cycle through both a vertebrate (human) and invertebrate (snail) host to complete the life cycle. My dissertation focuses on the genetic mechanisms...
Resource Type:: Dissertation
Full Text:: of my committee: Dee Denver, Dave Lytle, Gary Merrill, and Dave Shaw. I am grateful for their

ScholarsArchive@OSU

An assessment of the cardiac toxicity of compounds that cause methemoglobinemia using a non-vascularized fish heart model

Progress Towards the Total Synthesis of Bazzanin K

Structural effects on enzymatic activity of bacteriophage T4 lysozyme upon adsorption to colloidal silica

Search for protein-protein interactions underlying the cis-preferential replication of turnip yellow mosaic virus

Proteoglycans in the inner limiting membrane and their influence on axonal behavior in embryonic chicken retina

Molecular mechanisms of peroxisome proliferator-activated receptor signaling

Genetic aspects of sulfite tolerance in Saccharomyces cerevisiae

In vivo detoxification of acetic acid in Saccharomyces cerevisiae

Analysis of ras gene mutations in rainbow trout tumors

Genetic and phenotypic variation associated with the resistance gene SOD1 in Biomphalaria glabrata, an important intermediate host of Schistosomiasis

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