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Nongenomic action of progesterone inhibits oxytocin signaling through the ovine oxytocin receptor

Creator:

Bishop, Cecily V.

Abstract:

Experiments were conducted to characterize the nongenomic effects of progesterone (P4) on binding of oxytocin (OT) to the ovine oxytocin receptor (OTR) and signal transduction. The dose-response relationship of P4 to OT binding to the OTR in endometrium was examined. Progesterone interfered with the binding of OT to the OTR...

Resource Type:

Dissertation

Full Text:

Signaling Through The Ovine Oxytocin Receptor. Abstract Approved: Fredrick Stormshak