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Filtering by: Creator Morrow, Peter T. Remove constraint Creator: Morrow, Peter T. Committee Member Ostroverkhova, Oksana Remove constraint Committee Member: Ostroverkhova, Oksana

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  • Hydrogen/deuterium exchange mass spectrometry as a technology platform for studying conformational dynamics in large protein complexes

    Creator:
    Nirudodhi, Sasidhar N.
    Abstract:
    Proteins are essential to all biological systems. Proteins participate in numerous cellular processes by interacting with other proteins, other metabolites and membranes in a dynamic environment. Studying the structural and conformational properties of proteins in the solution phase is necessary to understand their protein folding and interaction dynamics. This research...
    Resource Type:
    Dissertation
    Full Text:
    . Victor Hsu, Dr. Vincent T. Remcho, Dr. Jan Frederik Stevens and Dr. Oksana Ostroverkhova. I would like

  • Efficient Private Matching for Private Databases

    Creator:
    Trieu, Thi Ni Ni
    Abstract:
    Private matching (PM) is a key cryptographic primitive in secure computation that allows several parties to jointly compute some functions depending on their private inputs. Indeed, this primitive has many practical applications. For instance, in online advertising, two companies may wish to find their common customers for a joint marketing...
    Resource Type:
    Dissertation
    Full Text:
    , Daniel Demm- ler, Vladimir Kolesnikov, Ranjit Kumaresan, Naor Matania, Benny Pinkas, Peter Rindal

  • Conformational Consequences: Calcium Regulates the Association Between Dysferlin C2A & PI(4,5)P2

    Creator:
    Otto, Shauna C.
    Abstract:
    Dysferlin is a ∼230 kDa terminally anchored membrane protein that is ubiquitously expressed, but is particularly enriched in skeletal and cardiac muscle tissue. Mutations covering the length of the protein have been linked to muscle wasting diseases including limb-girdle muscular dystrophy and Myoshi myopathy. Dysferlin has been shown to play...
    Resource Type:
    Dissertation
    Full Text:
    how Ca2+ binding can alter the properties of the domain. 9 T ab le 1. 1: C al ci u m b in d in

  • Cis-2,5-diaminobicyclo[2.2.2]octane : a novel C₂-symmetric scaffold for asymmetric catalysis

    Creator:
    Shaw, Subrata
    Abstract:
    This thesis describes the development of a new enantioselective synthetic method employing chiral cis-2,5-diaminobicyclo[2.2.2]octane-based organometallic catalysts. The significance of this new method to organic synthesis is illustrated with preparation of enantioenriched products that are transformed to important pharmaceutical agents. Chapter 1 provides a brief historical overview of asymmetric catalysis, especially...
    Resource Type:
    Dissertation
    Full Text:
    % ee 79% 1. L.CrCI (4 mol%) + 0 t-BuOMe, -35 to 5 °C Ph) 2. TfOH 28 0 Ph 32 L = 25: yield 85% L

  • Terahertz imaging and spectroscopy of carbon-based and semiconductor nanostructures

    Creator:
    Tomaino, Joseph L.
    Abstract:
    This thesis will cover work that I have completed relating to the field of terahertz (THz) science. My work has consisted of generating tunable, narrowband THz pulses in a table-top optical setup and using both narrow- and broadband THz pulses to study various material systems. Broadband THz pulses were used...
    Resource Type:
    Dissertation
    Full Text:
    Graphene+Si…..………………………….. 41 2.5 Transmission coefficient through a graphene thin film (t

  • Synthesis and Analysis of Heterostructural Semiconductor Alloy Sn1-xCaxCh (Ch=S, Se) and Nitrides Zn1-xWxN and Zn1-x(W1-yMoy)xN

    Creator:
    Matthews, Bethany E.
    Abstract:
    This work explores the synthesis and characterization of the metastable alloys Sn1-xCaxCh (Ch= S, Se) and nitride compounds Zn-W-Mo-N, which have recently been predicted by theorists. Single phase thin films of Sn1-xCaxS are prepared by pulsed laser deposition and radio-frequency magnetron sputtering and of Sn1-xCaxSe are prepared by pulsed laser...
    Resource Type:
    Dissertation
    Full Text:
    really helped me understand the equipment with your questions. I thank Peter Eschbach for always

  • Thermal conductivity measurements of amorphous metal thin films via the 3ω method

    Creator:
    Zhan, Kai
    Abstract:
    Amorphous multicomponent metals have promising applications in novel electronic devices because of their atomically smooth surface morphology and lack of grain boundaries. It is important to understand the thermal transport properties of amorphous metals and an accurate measurement of their thermal conductivity will be essential for further improvement of device...
    Resource Type:
    Masters Thesis
    Full Text:
    . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 4.1 Resistance R of heater in dependence of temperature T. Resistance during 3ω measurement

  • Multi-scale Investigation of Bidirectional Feedback Mechanism Between Breast Cancer Cells and Extracellular Matrix

    Creator:
    Kim, Jihan
    Abstract:
    Cell migration is fundamental for physiological processes such as immune re-sponses, wound healing and development. It is also a critical characteristic of metastatic cancer cells. An extensive amount of studies have focused on 2D sub-strates in order to understand the mechanism of cancer metastasis. However, much less is known about...
    Resource Type:
    Dissertation
    Full Text:
    persistent length lp , which are connected to each other. Each rod has radius of R. t⃗(s) represents

  • Functional Materials and Techniques for Additive Manufacturing in Soft Robotics

    Creator:
    Walker, Stephanie
    Abstract:
    This thesis outlines the development of new elastomeric materials and manufacturing processes for soft robotics. Specifically, this work describes the development of custom material formulations for use in additive manufacturing, additive manufacturing processing techniques for silicone elastomers, and multi-component additive manufacturing techniques. Material synthesis and processing is a gap in...
    Resource Type:
    Dissertation

  • Development of Cu-based Thin Films for Optoelectronic Applications

    Creator:
    Angelos, Gregory S.
    Abstract:
    CIGS and CdTe based commercial thin-film solar cells (TFSCs) require an absorber thickness greater than 2 µm and 4 µm, respectively, to adequately absorb the solar spectrum. To efficiently extract photoexcited electrons, these TFSCs require relatively defect-free absorbers with high-minority carrier mobility (> 100 cm2V−1s−1) and long lifetime (> 10...
    Resource Type:
    Dissertation
    Full Text:
    ) − 1 ] − Jph, (2.12) where kB is Boltzmann’s constant, T is temperature, n is the ideality factor, q