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Filtering by: Creator Naylor, Bridgett J. Committee Member Proteau, Philip Rights Statement In Copyright

New bioactive natural products from marine algae and cyanobacteria

Creator:

Sabry, Omar Mohamed

Abstract:

This thesis is an account of investigation on the natural products deriving from various marine algae and has resulted in the discovery of eleven novel bioactive metabolites. Isolation and characterization of these new molecules were carried out using different chromatographic techniques and by analyses of different spectroscopic data, respectively. Using...

Resource Type:

Dissertation

Full Text:

acid (4) H2N OOHOH OH OH HO 01- O "OH OH HO - 'OH HO OHOH Palytoxin (5) HO10 HO o HO J HO
Marine algal secondary metabolites of unique structure and biomedicinal or agrichemical potential

Creator:

Milligan, Kenneth Edward

Abstract:

This thesis describes investigations of marine algal secondary metabolites, with particular interest in their biomedical and agrichemical potential. Invaluable in such pursuits have been the access and application of advanced spectroscopic techniques, such as NMR, and the ability to assess the biological activity of the algal samples in a variety...

Resource Type:

Dissertation

Full Text:

, isolated and characterized malyngamides J and K. Dr. Michael Davies-Coleman facilitated and participated
The effect of ascorbate on enzymatic nitroglycerin bioactivation as measured by direct LC-MS/MS determination of nitrite

Creator:

Hardardt, Elizabeth Ann

Abstract:

This work sought to characterize a link between Vitamin C and nitroglycerin at the level of enzymatic bioactivation. Before we could proceed, we needed to develop a method that sensitively and selectively identified the product of bioactivation, nitrite. We successfully adapted traditional diaminonaphthalene derivatization with the use of stable isotope...

Resource Type:

Masters Thesis