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Filtering by: Creator Tran, Van Vinh Remove constraint Creator: Tran, Van Vinh Committee Member Qiu, Weihong Remove constraint Committee Member: Qiu, Weihong

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  • In vivo Reactions of Tetrazines Incorporated through Genetic Code Expansion

    Creator:
    Blizzard, Robert J.
    Abstract:
    The inverse electron demand Diels Alder reaction between tetrazines and strained alkenes is an exceptionally useful tool in functionalizing to biomolecules since it is orthogonal to the chemistry of most living systems and have exceptionally high rate constants. In particular reactions between strained trans-cyclooctenes (sTCO) and tetrazines can achieve second...
    Resource Type:
    Dissertation
    Full Text:
    annoy her. That person is Elise Van Fossen. Elise in particular, I have to thank for taking over for

  • Initial in vitro and in vivo Characterization of the Membrane Trafficking Protein Fer1L6

    Creator:
    Wolk, Chelsea
    Abstract:
    A fundamental difference between prokaryotic and eukaryotic cells is the presence of membrane bound organelles in eukaryotes. The dynamics of membrane trafficking within the cell are responsible for everything from intercellular communication and cell homeostasis, to mitosis, cell migration, and differentiation. These processes require exocytosis and compensatory endocytosis, often working...
    Resource Type:
    Dissertation
    Full Text:
    . Wang, M. van den Boogaard, L. Grand  Moursel, et al., Dysferlin regulates cell adhesion in human

  • Bridging the Gap Between Equilibrium Properties and Ultrafast Dynamics with Time-Resolved Spectroscopy of Functional Systems

    Creator:
    Krueger, Taylor D.
    Abstract:
    Ultrafast spectroscopy has recently gained momentum as a powerful, noninvasive characterization toolset capable of studying a diverse array of samples with applications in chemistry, physics, biology, engineering, and more. Two popular ultrafast spectroscopic techniques include femtosecond transient absorption (fs-TA) and femtosecond stimulated Raman spectroscopy (FSRS). The latter of these techniques...
    Resource Type:
    Dissertation
    Full Text:
    . Oksana Ostroverkhova, Dr. Seri Robinson, Dr. Gregory Giesbers, and Ray Van Court formed an excellent

  • Coulomb Explosion in Moderately Intense Nanosecond Laser Fields

    Creator:
    Yao, Yuzhong
    Abstract:
    In this dissertation, I present experimental observations of multiply charged atomic ions (MCAI) generated from interactions of atomic/molecular clusters with moderately intense nanosecond laser pulses. This process is also known as Coulomb explosion (CE) and it has been extensively studied in intense laser fields using ultrashort pulses. Several prevailing theories...
    Resource Type:
    Dissertation
    Full Text:
    Pandey, Mr. Steven Tran, and Ms. Kim Cuong Tran. My thanks also go to my dissertation committee: Dr

  • Dynamics and Design of Green Fluorescent Protein-Inspired Superphotoacids and Red-Emitting Fluorophores with Transient Absorption and Femtosecond Stimulated Raman Spectroscopy

    Creator:
    Chen, Cheng
    Abstract:
    In the past decades, femtosecond stimulated Raman spectroscopy (FSRS) has been gaining tremendous popularity in fundamental sciences stemming from chemistry to biology. It is capable of capturing both equilibrium and non-equilibrium structural information across a broad range of timescales with simultaneously high temporal and spectral resolutions. Femtosecond transient absorption spectroscopy...
    Resource Type:
    Dissertation

  • CoLocalized Excitation Emission Resolution : A CLEER approach for multicolor fluorescence analysis

    Creator:
    Almlie, C. Kyle
    Abstract:
    Fluorescence has proven to be a robust and powerful method of analysis in numerous fields: forensics, pharmaceutics, geology, food science, and environmental sciences have all developed a large collection of fluorescence instruments and methods to overcome application-specific challenges. Biological applications saw the same development of a fluorescence toolkit with methods...
    Resource Type:
    Dissertation

  • Nonlinear behavior of thermal and ion transport at the nanoscale

    Creator:
    Sahu, Subin
    Abstract:
    Functional control at the nanoscale forms the foundation of biological systems. These work at the cellular level by manipulating ions and molecules. Nanoscale devices that give functional control at this scale are also becoming an important component in diverse fields such as electronics, medicine, engineering, and manufacturing. Moreover, scientific advances...
    Resource Type:
    Dissertation
    Full Text:
    -bonded interactions include electrostatics interaction and van der Waals interaction. 11

  • Multicellular monolayer’s self-organization under external stimuli

    Creator:
    Li, Guanyu
    Abstract:
    Cell signaling under external stimulation is a critical mechanism that governs many biological processes such as cell proliferation, cell migration, and cell apoptosis, etc. For multicellular organisms, the ability to synchronize heterogeneous individual cellular responses through intercellular communication is crucial to maintain normal functionality. However, even though the biological pathways...
    Resource Type:
    Dissertation

  • Electron Diffraction of Neutral and Cationic Clusters Doped into Superfluid Helium Droplets

    Creator:
    Lei, Lei
    Abstract:
    In this dissertation, I describe the experimental investigation of electron diffraction of neutral and ionic clusters doped into superfluid helium droplets. The project is aimed at contributing to the development of an overall approach called ‘serial single molecule electron diffraction imaging (ss-EDI), a potential approach to solve macromolecule structures bypassing...
    Resource Type:
    Dissertation

  • Information Processing in Multicellular Networks

    Creator:
    Potter, Garrett D.
    Abstract:
    The ability for individual cells and multicellular networks to process information contained in perceived stimuli is of vital importance to their proper functioning and ultimately their cellular fate. The primary mechanism employed by cells to this end is the use of biochemical signaling in which a series of molecular events...
    Resource Type:
    Dissertation