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  • Regulation of mouse ribonucleotide reductase by allosteric effector-substrate interplay and hypoxia

    Creator:
    Chimploy, Korakod
    Abstract:
    In order to maintain genetic stability in eukaryotes, tight regulation of the relative sizes of deoxyribonucleoside triphosphate (dNTP) levels inside the cell is essential for optimal fidelity of DNA replication. Ribonucleotide reductase (RNR) is the enzyme responsible for proportional production of DNA precursors. Studies on regulation of this enzyme, the...
    Resource Type:
    Dissertation
    Full Text:
    genome (Jordan and Reichard, 1998). However, are the rates of synthesis and utilization always balanced

  • Molecular characterization of specificity and activity of the transposable element IS801

    Creator:
    Richter, Grace Yukiko
    Abstract:
    1S801 is a transposable element isolated from Pseudomonas syringae pathovar (pv.) phaseolicola, the causal agent of halo blight of bean. Fragments of the element are present in multiple copies on an indigenous plasmid, pMMC7105, of strain LR781, and have been implicated as sites of homologous recombination leading to imprecise excision...
    Resource Type:
    Dissertation
    Full Text:
    insertions of particular sequences found repeatedly, in different positions of the genome (Jordan et al

  • Diversity and Activity of Microbial Extracellular Peptidases in Soil

    Creator:
    Nguyen, Trang T. H.
    Abstract:
    Soil nitrogen exists largely as organic matter, including plant liter, dead animal matter, and microbial necromass. About 90% of soil organic nitrogen is proteinaceous material that is too large for plants and microorganisms to assimilate directly. Protein depolymerization therefore plays a critical role in mobilizing this organic source of nitrogen,...
    Resource Type:
    Dissertation
    Full Text:
    , Thuan Nguyen, Khoi Nguyen, Ni Trieu, Anh Ninh, Scott Jordan, Melanie Jordan, and many others for

  • Quorum sensing gene regulation in Pseudomonas aeruginosa

    Creator:
    Gupta, Rashmi
    Abstract:
    Pseudomonas aeruginosa is an opportunistic human pathogen that infects immunocompromised individuals such as those suffering from burns or the genetic disorder cystic fibrosis. This organism utilizes a cell-cell communication mechanism known as quorum sensing (QS) to coordinate virulence gene expression and biofilm formation. It has three interconnected QS systems, namely...
    Resource Type:
    Dissertation

  • Soil Solarization in Pacific Northwest Tree Seedling Nurseries: Effects on Soilborne Plant Pathogens, Soil Nutrients and the Soil Microbiome

    Creator:
    Weidman, Clara S.
    Abstract:
    Nursery and greenhouse products are economically important agricultural commodities for Oregon and Washington. Nursery crops including tree seedlings can be damaged or killed by soilborne plant pathogens, which can be challenging to manage because of their persistence in soil and limited options for control. Soil solarization is a pre-planting soil...
    Resource Type:
    Masters Thesis
    Full Text:
    , Caleb Trammell, Simon Fraher, Jordan Schweizer, Catherine Read, and other student workers who helped