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  • Molecular and genetic assessment of selected antiporters and methyl-accepting chemotaxis proteins in Vibrio cholerae

    Creator:
    Quinn, Matthew J.
    Abstract:
    The pathogen Vibrio cholerae uses cations as a primary currency of virulence and environmental persistence, using gradients of those cations to move, acquire nutrients, and control virulence gene expression. An understanding of the overlapping roles of bioenergetics and chemotaxis in the virulence and environmental survival of V. cholerae issues from...
    Resource Type:
    Dissertation
    Full Text:
    : Gitali Indra, Malcolm Lowry, Walt Ream, and Mahfuz Sarker. Pavel Dibrov has patiently, but

  • Cooperation and conflict in Pseudomonas aeruginosa quorum sensing

    Creator:
    Wilder, Cara N.
    Abstract:
    Pseudomonas aeruginosa is an environmental bacterium as well as an opportunistic pathogen that primarily infects immunocompromised individuals, including those suffering from cystic fibrosis. The density-dependent regulation of gene expression via cell-to-cell communication, also termed quorum sensing (QS), is an important virulence determinant in this organism. Generally, P. aeruginosa uses three...
    Resource Type:
    Dissertation
    Full Text:
    . Walt Ream, Jeff Chang, Susan Tornquist, and Mahfuz Sarker, who have generously given their time and