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Filtering by: Subject Electrostatics Committee Member Remcho, Vincent T.

Probing the Biophysical interactions of Anti-Microbial Peptide WLBU2 Using Model Membrane Systems

Creator:

Golbek, Thaddeus W.

Abstract:

WLBU2 is an engineered cationic amphiphilic peptide that targets Gram-positive and Gram-negative bacteria, and envelopes endotoxin while avoiding other cell types. The exact mechanism of how WLBU2 targets, binds, and disrupts bacterial cell membranes is still not completely known. Thus, the overall goal of this investigation is to determine the...

Resource Type:

Masters Thesis

Full Text:

binding between WLBU2 and cell membranes is induced by electrostatic interactions between charged amino